Halogen halos: Report of an early histopathologic finding in iododerma.


Journal

Journal of cutaneous pathology
ISSN: 1600-0560
Titre abrégé: J Cutan Pathol
Pays: United States
ID NLM: 0425124

Informations de publication

Date de publication:
Sep 2023
Historique:
revised: 05 06 2023
received: 18 01 2023
accepted: 13 06 2023
medline: 14 8 2023
pubmed: 3 7 2023
entrez: 3 7 2023
Statut: ppublish

Résumé

Iododerma is a rare cutaneous eruption that manifests after exposure to iodine-containing compounds, with few cases reported in the literature. Previous reports of this halogenoderma have described acellular halos simulating cryptococcus on histopathological examination but there is a paucity of reports of biopsies taken early in the disease course. We present a case of a 78-year-old patient who developed a papular eruption after receiving iodinated contrast. A skin biopsy taken within 24 h of the eruption showed a neutrophilic infiltrate with cryptococcal-like acellular haloed structures, indicating that the diagnostic finding may be found early in the disease course.

Identifiants

pubmed: 37394806
doi: 10.1111/cup.14489
doi:

Substances chimiques

Halogens 0

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

806-809

Informations de copyright

© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Références

Runge M, Williams K, Scharnitz T, et al. Iodine toxicity after iodinated contrast: new observations in iododerma. JAAD Case Rep. 2020;6(4):319-322. doi:10.1016/j.jdcr.2020.02.006
Hesseler MJ, Clark MR, Zacur JL, Rizzo JM, Hristov AC. An acneiform eruption secondary to iododerma. JAAD Case Rep. 2018;4(5):468-470. doi:10.1016/j.jdcr.2018.02.005
Ko JS, Fernandez AP, Anderson KA, et al. Morphologic mimickers of Cryptococcus occurring within inflammatory infiltrates in the setting of neutrophilic dermatitis: a series of three cases highlighting clinical dilemmas associated with a novel histopathologic pitfall. J Cutan Pathol. 2013;40(1):38-45. doi:10.1111/cup.12019
Byekova YA, Shedd AD, Schiro JA, Barrett TL, Lewin MR. An additional case of neutrophilic dermatosis histopathologically mimicking Cryptococcus in a patient with Sweet's syndrome. J Cutan Pathol. 2014;41(12):972-974. doi:10.1111/cup.12407
Wilson J, Gleghorn K, Kelly B. Cryptococcoid Sweet's syndrome: two reports of Sweet's syndrome mimicking cutaneous cryptococcosis. J Cutan Pathol. 2017;44(5):413-419. doi:10.1111/cup.12921
Fresco A, Wang J, Krausz A, et al. Cryptococcus-like changes in the setting of vasculitis. J Cutan Pathol. 2019;46(2):143-147. doi:10.1111/cup.13380

Auteurs

Avi Bitterman (A)

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Melissa Peri Zundell (MP)

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Corinna Psomadakis (C)

Department of Internal Medicine, Mount Sinai Morningside, New York, New York, USA.

Israel Kasago (I)

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Robert Phelps (R)

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

George Niedt (G)

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Saakshi Khattri (S)

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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Classifications MeSH