A coarse-grained molecular model of amyloid fibrils systems.

Amyloid / chemistry Models, Molecular Liquid Crystals / chemistry

Journal

Soft matter
ISSN: 1744-6848
Titre abrégé: Soft Matter
Pays: England
ID NLM: 101295070

Informations de publication

Date de publication:
12 Jul 2023
Historique:
medline: 13 7 2023
pubmed: 3 7 2023
entrez: 3 7 2023
Statut: epublish

Résumé

We report a computational model for amyloid fibrils and discuss its main features and ability to match different experimental morphological characteristics. The model captures the liquid crystalline and cholesteric behaviours in short and rigid amyloid fibrils and shows promising extendibility to more complex colloidal liquid crystals.

Identifiants

DOI: 10.1039/d3sm00408b PMID: 37395483
pubmed: 37395483
doi: 10.1039/d3sm00408b
doi:

Substances chimiques

Amyloid 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5044-5049

Auteurs

Shaden M Daghash (SM)

Department of Chemical Engineering, McGill University, 3610 University Street, Montréal, QC H3A 0C5, Canada. alejandro.rey@mcgill.ca.
ORCID: 0000-0002-9558-8702

Oscar M Matus Rivas (OM)

Department of Chemical Engineering, McGill University, 3610 University Street, Montréal, QC H3A 0C5, Canada. alejandro.rey@mcgill.ca.
ORCID: 0000-0001-5879-7778

Raffaele Mezzenga (R)

Department of Health Sciences and Technology, ETH Zürich, 8092 Zürich, Switzerland.
Department of Materials, ETH Zürich, 8093 Zürich, Switzerland.
ORCID: 0000-0002-5739-2610

Alejandro D Rey (AD)

Department of Chemical Engineering, McGill University, 3610 University Street, Montréal, QC H3A 0C5, Canada. alejandro.rey@mcgill.ca.
ORCID: 0000-0002-0440-8762

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Amyloïde › A coarse-grained molecular model of amyloid...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles moléculaires › A coarse-grained molecular model of amyloid...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Cristaux liquides › A coarse-grained molecular model of amyloid...