Use of a new non-contrast-enhanced BOOST cardiac MR sequence before electrical cardioversion or ablation of atrial fibrillation-a pilot study.

BOOST sequence ablation atrial fibrillation cardiac magnetic resonance imaging left atrial thrombus pulmonary vein anatomy

Journal

Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388

Informations de publication

Date de publication:
2023
Historique:
received: 01 03 2023
accepted: 24 05 2023
medline: 3 7 2023
pubmed: 3 7 2023
entrez: 3 7 2023
Statut: epublish

Résumé

Left atrial appendage (LAA) thrombus is the most common source of embolization in atrial fibrillation (AF). Transesophageal echocardiography (TEE) is the gold standard method for LAA thrombus exclusion. Our pilot study aimed to compare the efficacy of a new non-contrast-enhanced cardiac magnetic resonance (CMR) sequence (BOOST) with TEE for the detection of LAA thrombus and to evaluate the usefulness of BOOST images for planning radiofrequency catheter ablation (RFCA) compared with left atrial (LA) contrast-enhanced computed tomography (CT). We also attempted to assess the patients' subjective experiences with TEE and CMR. Patients with AF undergoing either electrical cardioversion or RFCA were enrolled. Participants underwent pre-procedural TEE and CMR scans to evaluate LAA thrombus status and pulmonary vein anatomy. Patient experiences with TEE and CMR were assessed using a questionnaire developed by our team. Some patients scheduled for RFCA also had pre-procedural LA contrast-enhanced CT. In such cases, the operating physician was asked to subjectively define the quality of the CT and CMR scan on a scale of 1-10 (1 = worst, 10 = best) and comment on CMR's usefulness in RFCA planning. Seventy-one patients were enrolled. In 94.4%, both TEE and CMR excluded, and in 1 patient, both modalities reported the presence of LAA thrombus. In 1 patient, TEE was inconclusive, but CMR excluded LAA thrombus. In 2 patients, CMR could not exclude the presence of thrombus, but in 1 of those cases, TEE was also indecisive. During TEE, 67%, during CMR, only 1.9% of patients reported pain ( The new CMR BOOST sequence provides appropriate image quality for ablation planning. The sequence might be useful for excluding larger LAA thrombi; however, its accuracy in detecting smaller thrombi is limited. Most patients preferred CMR over TEE in this indication.

Identifiants

pubmed: 37396587
doi: 10.3389/fcvm.2023.1177347
pmc: PMC10311645
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1177347

Informations de copyright

© 2023 Orbán, Dohy, Suhai, Nagy, Salló, Boga, Kiss, Kunze, Neji, Botnar, Prieto, Gellér, Merkely, Vágó and Szegedi.

Déclaration de conflit d'intérêts

KK, RN, and MK are employees of Siemens Healthineers. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Gábor Orbán (G)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Zsófia Dohy (Z)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Ferenc Imre Suhai (FI)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Anikó Ilona Nagy (AI)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Zoltán Salló (Z)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Márton Boga (M)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Máté Kiss (M)

Siemens Healthcare Hungary, Budapest, Hungary.

Karl Kunze (K)

MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom.

Radhouene Neji (R)

MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom.

Rene Botnar (R)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile.

Claudia Prieto (C)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile.

László Gellér (L)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Béla Merkely (B)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Hajnalka Vágó (H)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Nándor Szegedi (N)

Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Classifications MeSH