Patterns of foot-and-mouth disease virus detection in environmental samples in an endemic setting.
Bayesian analysis
disease modeling
endemic FMD
environment
viral RNA detection
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2023
2023
Historique:
received:
02
02
2023
accepted:
29
05
2023
medline:
3
7
2023
pubmed:
3
7
2023
entrez:
3
7
2023
Statut:
epublish
Résumé
Foot-and-Mouth Disease virus (FMDV) is endemic in several regions and is a virus that can persist in the environment dependent on pH, relative humidity (RH), temperature, and matrix (i.e., soil, water, or air). Our previously published analysis of available viral persistence data showed that persistence is likely affected by interactions between RH, temperature, and matrix. Understanding these relationships will aid efforts to eliminate FMD, which has significant impacts on economies and food security. In Cameroon, West Africa, the livestock system consists of mobile (transhumant), transboundary trade and sedentary herds. Studying this system can provide information about the patterns of environmental detection of FMDV RNA that may influence approaches to virus elimination on premises during an outbreak. To improve our understanding of these patterns, we collected samples from individuals, vehicles, and along cattle pathways at three sedentary herds beginning on day one of owner-reported outbreaks, ending by day 30, and tested for the presence of FMD viral RNA using rRT-PCR. Our analysis suggests that detection decreases in soil surface samples with increased distance from herd and time from the first report of disease. Whereas time but not distance decreases detection in air samples. Interaction of RH and temperature suggests increased detection at high temperatures (>24°C) and RH (>75%), providing us with new information about the patterns of FMD viral RNA detection in and around cattle herds that could help to inform targeted virus elimination strategies, such as location and application of disinfectants.
Identifiants
pubmed: 37396995
doi: 10.3389/fvets.2023.1157538
pmc: PMC10312077
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1157538Informations de copyright
Copyright © 2023 Mielke, Lendzele, Delgado, Abdoulmoumini, Dickmu and Garabed.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Gen Virol. 1972 Apr;15(1):25-33
pubmed: 4337217
Prev Vet Med. 2013 Apr 1;109(1-2):10-24
pubmed: 22995473
J Am Vet Med Assoc. 2002 Jun 1;220(11):1636-42
pubmed: 12051502
Vet Rec. 2001 May 12;148(19):602-4
pubmed: 11386448
J Gen Virol. 1973 Sep;20(3):311-8
pubmed: 4355328
Transbound Emerg Dis. 2020 Mar;67(2):543-554
pubmed: 31595659
Prev Vet Med. 2016 Jan 1;123:1-11
pubmed: 26718055
Front Vet Sci. 2017 Jul 24;4:118
pubmed: 28791298
mBio. 2020 Aug 4;11(4):
pubmed: 32753488
Transbound Emerg Dis. 2008;55(1):73-87
pubmed: 18397510
Appl Environ Microbiol. 2018 Aug 1;84(16):
pubmed: 29959244
Rev Sci Tech. 2015 Dec;34(3):895-905
pubmed: 27044160
J Gen Virol. 1972 Apr;15(1):17-24
pubmed: 4337216
Transbound Emerg Dis. 2022 Sep;69(5):3041-3046
pubmed: 34331827
Naturwissenschaften. 2008 Jun;95(6):483-91
pubmed: 18320161
PLoS One. 2021 Jan 28;16(1):e0244977
pubmed: 33507951
Vet Res. 2015 Apr 17;46:43
pubmed: 25928658
Front Vet Sci. 2018 May 04;5:78
pubmed: 29780811
Viruses. 2022 May 09;14(5):
pubmed: 35632750
Proc Soc Exp Biol Med. 1957 May;95(1):147-52
pubmed: 13432017