Krause corpuscles of the genitalia are vibrotactile sensors required for normal sexual behavior.


Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
15 Jun 2023
Historique:
pubmed: 3 7 2023
medline: 3 7 2023
entrez: 3 7 2023
Statut: epublish

Résumé

Krause corpuscles, first discovered in the 1850s, are enigmatic sensory structures with unknown physiological properties and functions found within the genitalia and other mucocutaneous tissues. Here, we identified two distinct somatosensory neuron subtypes that innervate Krause corpuscles of the mouse penis and clitoris and project to a unique sensory terminal region of the spinal cord. Using

Identifiants

pubmed: 37398085
doi: 10.1101/2023.06.14.545006
pmc: PMC10312780
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NCCIH NIH HHS
ID : R01 AT011447
Pays : United States
Organisme : NINDS NIH HHS
ID : R35 NS097344
Pays : United States

Déclaration de conflit d'intérêts

Competing interests: The authors have no competing interests.

Auteurs

Lijun Qi (L)

Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115.

Michael Iskols (M)

Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115.

Annie Handler (A)

Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115.

David D Ginty (DD)

Department of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115.

Classifications MeSH