Pregnancy outcomes in in vitro fertilization in 17-alpha-hydroxylase deficiency.
17-alpha-hydroxylase deficiency
congenital adrenal hyperplasia
hormone replacement therapy
infertility
in vitro fertilization
Journal
F&S reports
ISSN: 2666-3341
Titre abrégé: F S Rep
Pays: United States
ID NLM: 101766618
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
22
09
2022
revised:
23
02
2023
accepted:
24
02
2023
medline:
3
7
2023
pubmed:
3
7
2023
entrez:
3
7
2023
Statut:
epublish
Résumé
Since the first case of 17-alpha-hydroxylase-deficiency (17-OHD) was described in 1966, a number of cases have been reported with a clinical picture of hypertension, hypokalemia, and hypogonadism. Infertility is a major concern for some of these individuals. This mini-review aims to detail the components of this disorder that affect fertility and focus on the recent acceleration in the success of achieving live births, as well as highlight the unsuccessful attempts. The data supporting successful live births remains limited, but existing evidence suggests that in vitro fertilization can be used in conjunction with hormone replacement therapy and steroid suppression to achieve live birth in patients with infertility from 17-OHD.
Identifiants
pubmed: 37398620
doi: 10.1016/j.xfre.2023.02.012
pii: S2666-3341(23)00031-4
pmc: PMC10310957
doi:
Types de publication
Journal Article
Langues
eng
Pagination
144-149Informations de copyright
© 2023 The Authors.
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