Quality of life in bladder cancer: systematic review and meta-analysis.

quality of life

Journal

BMJ supportive & palliative care
ISSN: 2045-4368
Titre abrégé: BMJ Support Palliat Care
Pays: England
ID NLM: 101565123

Informations de publication

Date de publication:
03 Jul 2023
Historique:
received: 26 01 2023
accepted: 23 05 2023
medline: 4 7 2023
pubmed: 4 7 2023
entrez: 3 7 2023
Statut: aheadofprint

Résumé

Worldwide, bladder cancer (BC) has been regarded as the tenth most common cancer with more than 573 000 new cases in 2020. This research presents a systematic review and meta-analysis of studies examining the quality of life (QOL) among patients with BC. The study was designed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A total of 11 articles were extracted from a literature search conducted through electronic databases including PubMed, EMBASE, Scopus and Web of Science from the onset of January 2000 to June 2022. A random-effects model was applied to estimate the pooled QOL in patients with BC. We included 11 primary studies in the final meta-analysis. Based on random effect analysis, total score of QOL was 53.92 (95% CI: 47.84 to 60) representing a moderate level of QOL among patients. Based on the analysis, it was found that physical items with a score of 49.82 (95% CI: 45.8 to 53.84) had a lower score in comparison with mental items at a score of 52 (95% CI: 49.54 to 54.47). In addition, the item of role limitations due to physical health with a score of 46.26 (95% CI: 20.11 to 72.41), and social functioning with a score of 46.25 (95% CI: 18.85 to 73.66), respectively, had the lowest QOL in patients with BC. Generally, the QOL among patients with BC was in a moderate condition, which can be improved through determining the influencing factors on QOL as a crucial strategy to define future treatment procedures in an effective manner.

Sections du résumé

BACKGROUND BACKGROUND
Worldwide, bladder cancer (BC) has been regarded as the tenth most common cancer with more than 573 000 new cases in 2020. This research presents a systematic review and meta-analysis of studies examining the quality of life (QOL) among patients with BC.
METHODS METHODS
The study was designed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A total of 11 articles were extracted from a literature search conducted through electronic databases including PubMed, EMBASE, Scopus and Web of Science from the onset of January 2000 to June 2022. A random-effects model was applied to estimate the pooled QOL in patients with BC.
RESULTS RESULTS
We included 11 primary studies in the final meta-analysis. Based on random effect analysis, total score of QOL was 53.92 (95% CI: 47.84 to 60) representing a moderate level of QOL among patients. Based on the analysis, it was found that physical items with a score of 49.82 (95% CI: 45.8 to 53.84) had a lower score in comparison with mental items at a score of 52 (95% CI: 49.54 to 54.47). In addition, the item of role limitations due to physical health with a score of 46.26 (95% CI: 20.11 to 72.41), and social functioning with a score of 46.25 (95% CI: 18.85 to 73.66), respectively, had the lowest QOL in patients with BC.
CONCLUSION CONCLUSIONS
Generally, the QOL among patients with BC was in a moderate condition, which can be improved through determining the influencing factors on QOL as a crucial strategy to define future treatment procedures in an effective manner.

Identifiants

pubmed: 37400163
pii: spcare-2023-004185
doi: 10.1136/spcare-2023-004185
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Sima Rafiei (S)

Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran (the Islamic Republic of).

Golnaz Kheradkhah (G)

The School of Medicine, Dentistry & Nursing, University of Glasgow, Glasgow, UK.

Grigorios Kotronoulas (G)

The School of Medicine, Dentistry & Nursing, University of Glasgow, Glasgow, UK.

Maryam Doustmehraban (M)

Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran (the Islamic Republic of).

Farnoosh Shafiei (F)

Student Research Committee, Faculty of Health Management and Information Sciences Branch, Iran University of Medical Sciences, Tehran, Iran.

Maryam Masoumi (M)

Clinical research and development center, Qom University of Medical Sciences, Qom, Iran.

Elaheh Parnian (E)

Student Research Committee, Faculty of Health Management and Information Sciences Branch, Iran University of Medical Sciences, Tehran, Iran.

Elmira Nosrati Sanjabad (E)

Student Research Committee, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.

Ahmad Ghashghaee (A)

Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran (the Islamic Republic of) ahmad.ghashghaee1996@gmail.com.
The School of Medicine, Dentistry & Nursing, University of Glasgow, Glasgow, UK.

Classifications MeSH