Interchangeable Role of Motor Cortex and Reafference for the Stable Execution of an Orofacial Action.
efference copy
internal model
motor cortex
red nucleus
sensorimotor
vibrissa
whisker
Journal
The Journal of neuroscience : the official journal of the Society for Neuroscience
ISSN: 1529-2401
Titre abrégé: J Neurosci
Pays: United States
ID NLM: 8102140
Informations de publication
Date de publication:
26 07 2023
26 07 2023
Historique:
received:
31
10
2022
revised:
25
06
2023
accepted:
27
06
2023
pmc-release:
26
01
2024
medline:
28
7
2023
pubmed:
4
7
2023
entrez:
3
7
2023
Statut:
ppublish
Résumé
Animals interact with their environment through mechanically active, mobile sensors. The efficient use of these sensory organs implies the ability to track their position; otherwise, perceptual stability or prehension would be profoundly impeded. The nervous system may keep track of the position of a sensorimotor organ via two complementary feedback mechanisms-peripheral reafference (external, sensory feedback) and efference copy (internal feedback). Yet, the potential contributions of these mechanisms remain largely unexplored. By training male rats to place one of their vibrissae within a predetermined angular range without contact, a task that depends on knowledge of vibrissa position relative to their face, we found that peripheral reafference is not required. The presence of motor cortex is not required either, except in the absence of peripheral reafference to maintain motor stability. Finally, the red nucleus, which receives descending inputs from motor cortex and cerebellum and projects to facial motoneurons, is critically involved in the execution of the vibrissa positioning task. All told, our results point toward the existence of an internal model that requires either peripheral reafference or motor cortex to optimally drive voluntary motion.
Identifiants
pubmed: 37400255
pii: JNEUROSCI.2089-22.2023
doi: 10.1523/JNEUROSCI.2089-22.2023
pmc: PMC10376937
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
5521-5536Subventions
Organisme : NINDS NIH HHS
ID : U01 NS090595
Pays : United States
Organisme : NINDS NIH HHS
ID : U19 NS107466
Pays : United States
Informations de copyright
Copyright © 2023 the authors.
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