The Gambia Trachomatous Trichiasis Surveys: Results from Five Evaluation Units Confirm Attainment of Trachoma Elimination Thresholds.

Elimination Epidemiology Survey The Gambia Trachomatous trichiasis

Journal

Ophthalmic epidemiology
ISSN: 1744-5086
Titre abrégé: Ophthalmic Epidemiol
Pays: England
ID NLM: 9435674

Informations de publication

Date de publication:
03 Jul 2023
Historique:
medline: 4 7 2023
pubmed: 4 7 2023
entrez: 4 7 2023
Statut: aheadofprint

Résumé

Trichiasis is present when in-turned eyelashes touch the eyeball. It may result in permanent vision loss. Trachomatous trichiasis (TT) is caused by multiple rounds of inflammation associated with conjunctival Chlamydia trachomatis infection. Surveys have been designed to estimate the prevalence of TT in evaluation units (EUs) of trachoma-endemic countries in order to help develop appropriate programme-level plans. In this study, TT-only surveys were conducted in five EUs of The Gambia to determine whether further intensive programmatic action was required. Two-stage cluster sampling was used to select 27 villages per EU and ~25 households per village. Graders assessed the TT status of individuals aged ≥15 years in each selected household, including the presence or absence of conjunctival scarring in those with TT. From February to March 2019, 11595 people aged ≥15 years were examined. A total of 34 cases of TT were identified. All five EUs had an age- and gender-adjusted prevalence of TT unknown to the health system <0.2%. Three of five EUs had a prevalence of 0.0%. Using these and other previously collected data, in 2021, The Gambia was validated as having achieved national elimination of trachoma as a public health problem. Trachoma is still present in the population, but as its prevalence is low, it is unlikely that today's youth will experience the exposure to C. trachomatis required to precipitate TT. The Gambia demonstrates that with political will and consistent application of human and financial resources, trachoma can be eliminated as a public health problem.

Identifiants

pubmed: 37401113
doi: 10.1080/09286586.2023.2213320
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-9

Subventions

Organisme : World Health Organization
ID : 001
Pays : International

Auteurs

Sarjo Kanyi (S)

The National Eye Health Programme, Ministry of Health, Banjul, Kanifing, The Gambia.

Abba Hydara (A)

Sheikh Zayed Regional Eye Care Center, Banjul, Kanifing, The Gambia.

Ansumana Sillah (A)

The National Eye Health Programme, Ministry of Health, Banjul, Kanifing, The Gambia.

Caleb Mpyet (C)

Department of Ophthalmology, University of Jos, Jos, Nigeria.
Sightsavers Nigeria Country Office, Kaduna, Nigeria.

Anna Harte (A)

Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.

Ana Bakhtiari (A)

International Trachoma Initiative, Task Force for Global Health, Atlanta, Georgia, USA.

Rebecca Willis (R)

International Trachoma Initiative, Task Force for Global Health, Atlanta, Georgia, USA.

Cristina Jimenez (C)

Sightsavers International, Sightsavers, Haywards Heath, UK.

Agatha Aboe (A)

Department of Ophthalmology, University of Jos, Jos, Nigeria.

Robin Bailey (R)

Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.

Emma M Harding-Esch (EM)

Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.

Anthony W Solomon (AW)

Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.

Balla Musa Joof (BM)

Sightsavers, Banjul, The Gambia.

Classifications MeSH