Nutrigenomics of inward rectifier potassium channels.

Potassium Channels, Inwardly Rectifying / genetics Nutrigenomics Membrane Potentials KATP Channels Potassium / metabolism
Inward rectifier potassium channels Ion channels Metabolism Nutrigenomics Potassium channels

Journal

Biochimica et biophysica acta. Molecular basis of disease
ISSN: 1879-260X
Titre abrégé: Biochim Biophys Acta Mol Basis Dis
Pays: Netherlands
ID NLM: 101731730

Informations de publication

Date de publication:
10 2023
Historique:
received: 20 03 2023
revised: 27 06 2023
accepted: 30 06 2023
medline: 7 8 2023
pubmed: 6 7 2023
entrez: 5 7 2023
Statut: ppublish

Résumé

Inwardly rectifying potassium (Kir) channels play a key role in maintaining the resting membrane potential and supporting potassium homeostasis. There are many variants of Kir channels, which are usually tetramers in which the main subunit has two trans-membrane helices attached to two N- and C-terminal cytoplasmic tails with a pore-forming loop in between that contains the selectivity filter. These channels have domains that are strongly modulated by molecules present in nutrients found in different diets, such as phosphoinositols, polyamines and Mg

Identifiants

DOI: 10.1016/j.bbadis.2023.166803 PMID: 37406972
pubmed: 37406972
pii: S0925-4439(23)00169-2
doi: 10.1016/j.bbadis.2023.166803
pii:
doi:

Substances chimiques

Potassium Channels, Inwardly Rectifying 0
KATP Channels 0
Potassium RWP5GA015D

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

166803

Informations de copyright

Copyright © 2023. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors confirm that there is no conflict of interest.

Auteurs

Gonzalo Ferreira (G)

Laboratory of Ion Channels, Biological Membranes and Cell Signaling, Dept. of Biophysics, Facultad de Medicina, CP 11800, Universidad de la Republica, Montevideo, Uruguay. Electronic address: ferreira@fmed.edu.uy.

Axel Santander (A)

Laboratory of Ion Channels, Biological Membranes and Cell Signaling, Dept. of Biophysics, Facultad de Medicina, CP 11800, Universidad de la Republica, Montevideo, Uruguay.

Romina Cardozo (R)

Laboratory of Ion Channels, Biological Membranes and Cell Signaling, Dept. of Biophysics, Facultad de Medicina, CP 11800, Universidad de la Republica, Montevideo, Uruguay.

Luisina Chavarría (L)

Laboratory of Ion Channels, Biological Membranes and Cell Signaling, Dept. of Biophysics, Facultad de Medicina, CP 11800, Universidad de la Republica, Montevideo, Uruguay.

Lucía Domínguez (L)

Laboratory of Ion Channels, Biological Membranes and Cell Signaling, Dept. of Biophysics, Facultad de Medicina, CP 11800, Universidad de la Republica, Montevideo, Uruguay.

Nicolás Mujica (N)

Laboratory of Ion Channels, Biological Membranes and Cell Signaling, Dept. of Biophysics, Facultad de Medicina, CP 11800, Universidad de la Republica, Montevideo, Uruguay.

Milagros Benítez (M)

Laboratory of Ion Channels, Biological Membranes and Cell Signaling, Dept. of Biophysics, Facultad de Medicina, CP 11800, Universidad de la Republica, Montevideo, Uruguay.

Santiago Sastre (S)

Laboratory of Ion Channels, Biological Membranes and Cell Signaling, Dept. of Biophysics, Facultad de Medicina, CP 11800, Universidad de la Republica, Montevideo, Uruguay; Centro de Investigaciones Biomédicas (CEINBIO), Universidad de la República, Montevideo CP 11800, Uruguay.

Luis Sobrevia (L)

Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8330024, Chile; Department of Physiology, Faculty of Pharmacy, Universidad de Sevilla, Seville E-41012, Spain; Medical School (Faculty of Medicine), Sao Paulo State University (UNESP), Brazil; Centre for Clinical Research (UQCCR), Faculty of Medicine and Biomedical Sciences, University of Queensland, Herston, 4029, Queensland, Australia; Tecnologico de Monterrey, Eutra, The Institute for Obesity Research (IOR), School of Medicine and Health Sciences, Monterrey, Nuevo León, Mexico.

Garth L Nicolson (GL)

Department of Molecular Pathology, The Institute for Molecular Medicine, Huntington Beach, CA, USA.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Canaux potassiques rectifiants entrants › Nutrigenomics of inward rectifier potassium channels.
questionsmedicales.fr › Professions de santé › Sciences de la nutrition › Nutrigénomique › Nutrigenomics of inward rectifier potassium channels.
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Potentiels de membrane › Nutrigenomics of inward rectifier potassium channels.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Canaux potassiques rectifiants entrants › Canaux KATP › Nutrigenomics of inward rectifier potassium channels.
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux légers › Potassium › Nutrigenomics of inward rectifier potassium channels.