The European Society for Blood and Marrow Transplantation (EBMT) roadmap and perspectives to improve nutritional care in patients undergoing hematopoietic stem cell transplantation on behalf of the Cellular Therapy and Immunobiology Working Party (CTIWP) and the Nurses Group (NG) of the EBMT.
Journal
Bone marrow transplantation
ISSN: 1476-5365
Titre abrégé: Bone Marrow Transplant
Pays: England
ID NLM: 8702459
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
received:
04
02
2023
accepted:
07
06
2023
revised:
10
05
2023
medline:
4
9
2023
pubmed:
6
7
2023
entrez:
5
7
2023
Statut:
ppublish
Résumé
Malnutrition is the most common comorbidity during the continuum of hematopoietic stem cell transplant (HSCT) and negatively impacts clinical outcomes, response to therapy, quality of life, and costs. The intensive conditioning regimen administered before transplant causes inflammatory damages to the gastrointestinal system, which themselves contribute to trigger graft versus host disease (GvHD) in the allogeneic setting. GvHD and other post-transplant complications such as infections adversely affect food intake and gut absorption of nutrients. Consequently, patients exhibit signs of malnutrition such as weight loss and muscle wasting, thus triggering a "vicious circle" that favours additional complications. Among HSCT centres, there is marked variability in nutritional care, from screening for malnutrition to nutritional intervention. The present paper, elaborated by the Cellular Therapy and Immunobiology Working Party and the Nurses Group of the European Society for Blood and Marrow Transplantation, aims at defining a roadmap that identifies the main nutritional critical issues in the field of HSCT. This document will be propaedeutic to the development of clinical algorithms to counteract risk factors of malnutrition, based on scientific evidence and shared among HSCT centres, and thus maximize transplant outcomes.
Identifiants
pubmed: 37407728
doi: 10.1038/s41409-023-02018-z
pii: 10.1038/s41409-023-02018-z
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
965-972Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature Limited.
Références
Copelan EA. Hematopoietic stem-cell transplantation. N. Engl J Med. 2006;354:1813–26. https://doi.org/10.1056/NEJMra052638 .
doi: 10.1056/NEJMra052638
pubmed: 16641398
Fuji S, Einsele H, Savani BN, Kapp M. Systematic nutritional support in allogeneic hematopoietic stem cell transplant recipients. Biol Blood Marrow Transpl. 2015;21:1707–13. https://doi.org/10.1016/j.bbmt.2015.07.003 .
doi: 10.1016/j.bbmt.2015.07.003
‘Contemporary Bone marrow transplantation’ (2021) Organ and Tissue Transplantation. https://doi.org/10.1007/978-3-030-36358-1 .
Price S, Kim Y. Body composition impacts hematopoietic stem cell transplant outcomes in both autologous and allogeneic transplants: a systematic review. Nutr Cancer. 2022;74:2731–47. https://doi.org/10.1080/01635581.2021.2020303 .
doi: 10.1080/01635581.2021.2020303
pubmed: 34963380
Eglseer D, Bauer S, Huber-Kraßnitzer B, Greinix H. Malnutrition risk prior to hematopoietic stem cell transplantation predicts mortality in adults. Bone Marrow Transpl. 2021;56:2268–71. https://doi.org/10.1038/s41409-021-01292-z .
doi: 10.1038/s41409-021-01292-z
Caccialanza R, Cereda E, Pinto C, Cotogni P, Farina G, Gavazzi C, et al. Awareness and consideration of malnutrition among oncologists: Insights from an exploratory survey. Nutrition. 2016;32:1028–32. https://doi.org/10.1016/j.nut.2016.02.005 .
doi: 10.1016/j.nut.2016.02.005
pubmed: 27066746
Caccialanza R, Lobascio F, Cereda E, Aprile G, Farina G, Traclò F, et al. Cancer-related malnutrition management: A survey among Italian Oncology Units and Patients’ Associations. Curr Probl Cancer. 2020;44:100554. https://doi.org/10.1016/j.currproblcancer.2020.100554 .
doi: 10.1016/j.currproblcancer.2020.100554
pubmed: 32024589
Caccialanza R, Goldwasser F, Marschal O, Ottery F, Schiefke I, Tilleul P, et al. Unmet needs in clinical nutrition in oncology: a multinational analysis of real-world evidence. Ther Adv Med Oncol. 2020;12:1758835919899852. https://doi.org/10.1177/1758835919899852 .
doi: 10.1177/1758835919899852
pubmed: 32110247
pmcid: 7025419
Peric Z, Botti S, Stringer J, Krawczyk J, van der Werf S, van Biezen A, et al. Variability of nutritional practices in peritransplant period after allogeneic hematopoietic stem cell transplantation: a survey by the Complications and Quality of Life Working Party of the EBMT. Bone Marrow Transpl. 2018;53:1030–7. https://doi.org/10.1038/s41409-018-0137-1 .
doi: 10.1038/s41409-018-0137-1
Caccialanza R, De Lorenzo F, Gianotti L, Zagonel V, Gavazzi C, Farina G, et al. Nutritional support for cancer patients: still a neglected right? Support Care Cancer. 2017;25:3001–4. https://doi.org/10.1007/s00520-017-3826-1 .
doi: 10.1007/s00520-017-3826-1
pubmed: 28710645
Brotelle T, Lemal R, Cabrespine A, Combal C, Hermet E, Ravinet A, et al. Prevalence of malnutrition in adult patients previously treated with allogeneic hematopoietic stem-cell transplantation. Clin Nutr. 2018;37:739–45. https://doi.org/10.1016/j.clnu.2017.03.016 .
doi: 10.1016/j.clnu.2017.03.016
pubmed: 28390845
Urbain P, Birlinger J, Lambert C, Finke J, Bertz H, Biesalski HK. Longitudinal follow-up of nutritional status and its influencing factors in adults undergoing allogeneic hematopoietic cell transplantation. Bone Marrow Transpl. 2013;48:446–51. https://doi.org/10.1038/bmt.2012.158 .
doi: 10.1038/bmt.2012.158
Inzucchi SE. Clinical practice. Management of hyperglycemia in the hospital setting. N. Engl J Med. 2006;355:1903–11. https://doi.org/10.1056/NEJMcp060094 .
doi: 10.1056/NEJMcp060094
pubmed: 17079764
Cederholm T, Barazzoni R, Austin P, Ballmer P, Biolo G, Bischoff SC, et al. ESPEN guidelines on definitions and terminology of clinical nutrition. Clin Nutr. 2017;36:49–64. https://doi.org/10.1016/j.clnu.2016.09.004 .
doi: 10.1016/j.clnu.2016.09.004
pubmed: 27642056
Thibault R, Genton L, Pichard C. Body composition: why, when and for who? Clin Nutr. 2012;31:435–47. https://doi.org/10.1016/j.clnu.2011.12.011 .
doi: 10.1016/j.clnu.2011.12.011
pubmed: 22296871
Ravasco P. Nutrition in cancer patients. J Clin Med. 2019;8:1211. https://doi.org/10.3390/jcm8081211 .
doi: 10.3390/jcm8081211
pubmed: 31416154
pmcid: 6723589
Zou J-Y, Li Y-Y, Gu Y, Ling C-J. Changes in body composition of patients with acute leukemia during induction and consolidation chemotherapies. https://doi.org/10.21203/rs.3.rs1368482/v1 .
Morishita S, Tsubaki A, Hotta K, Fu JB, Fuji S. The benefit of exercise in patients who undergo allogeneic hematopoietic stem cell transplantation. J Int Soc Phys Rehabil Med. 2019;2:54–61. https://doi.org/10.4103/jisprm.jisprm_2_19 .
doi: 10.4103/jisprm.jisprm_2_19
pubmed: 31131374
pmcid: 6532661
Tanaka S, Imataki O, Kitaoka A, Fujioka S, Hanabusa E, Ohbayashi Y, et al. Clinical impact of sarcopenia and relevance of nutritional intake in patients before and after allogeneic hematopoietic stem cell transplantation. J Cancer Res Clin Oncol. 2017;143:1083–92. https://doi.org/10.1007/s00432-016-2336-8 .
doi: 10.1007/s00432-016-2336-8
pubmed: 28224299
Bassim CW, Fassil H, Dobbin M, Steinberg SM, Baird K, Cole K, et al. Malnutrition in patients with chronic GVHD. Bone Marrow Transpl. 2014;49:1300–6. https://doi.org/10.1038/bmt.2014.145 .
doi: 10.1038/bmt.2014.145
Sorror ML, Maris MB, Storb R, Baron F, Sandmaier BM, Maloney DG, et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood. 2005;106:2912–9. https://doi.org/10.1182/blood-2005-05-2004 .
doi: 10.1182/blood-2005-05-2004
pubmed: 15994282
pmcid: 1895304
Majhail NS, Flowers ME, Ness KK, Jagasia M, Carpenter PA, Arora M, et al. High prevalence of metabolic syndrome after allogeneic hematopoietic cell transplantation. Bone Marrow Transpl. 2009;43:49–54. https://doi.org/10.1038/bmt.2008.263 .
doi: 10.1038/bmt.2008.263
Bargetzi L, Brack C, Herrmann J, Bargetzi A, Hersberger L, Bargetzi M, et al. Nutritional support during the hospital stay reduces mortality in patients with different types of cancers: secondary analysis of a prospective randomized trial. Ann Oncol. 2021;32:1025–33. https://doi.org/10.1016/j.annonc.2021.05.793 .
doi: 10.1016/j.annonc.2021.05.793
pubmed: 34022376
Beckerson J, Szydlo RM, Hickson M, Mactier CE, Innes AJ, Gabriel IH, et al. Impact of route and adequacy of nutritional intake on outcomes of allogeneic haematopoietic cell transplantation for haematologic malignancies. Clin Nutr. 2019;38:738–44. https://doi.org/10.1016/j.clnu.2018.03.008 .
doi: 10.1016/j.clnu.2018.03.008
pubmed: 29650256
Muscaritoli M, Arends J, Bachmann P, Baracos V, Barthelemy N, Bertz H, et al. ESPEN practical guideline: Clinical Nutrition in cancer. Clin Nutr. 2021;40:2898–913. https://doi.org/10.1016/j.clnu.2021.02.005 .
doi: 10.1016/j.clnu.2021.02.005
pubmed: 33946039
Cederholm T, Jensen GL, Correia MITD, Gonzalez MC, Fukushima R, Higashiguchi T. et al. GLIM criteria for the diagnosis of malnutrition—A consensus report from the global clinical nutrition community. Clin Nutr. 2019;38:1–9. https://doi.org/10.1016/j.clnu.2018.08.002 .
doi: 10.1016/j.clnu.2018.08.002
pubmed: 30181091
Prado CM, Landi F, Chew STH, Atherton PJ, Molinger J, Ruck T, et al. Advances in muscle health and nutrition: a toolkit for healthcare professionals. Clin Nutr. 2022;41:2244–63. https://doi.org/10.1016/j.clnu.2022.07.041 .
doi: 10.1016/j.clnu.2022.07.041
pubmed: 36081299
Piccoli A, Rossi B, Pillon L, Bucciante G. A new method for monitoring body fluid variation by bioimpedance analysis: the RXc graph. Kidney Int. 1994;46:534–9. https://doi.org/10.1038/ki.1994.305 .
doi: 10.1038/ki.1994.305
pubmed: 7967368
Caccialanza R, Cotogni P, Cereda E, Bossi P, Aprile G, Delrio P, et al. Nutritional Support in Cancer patients: update of the Italian Intersociety Working Group practical recommendations. J Cancer. 2022;13:2705–16. https://doi.org/10.7150/jca.73130 .
doi: 10.7150/jca.73130
pubmed: 35812181
pmcid: 9254882
Jabbour J, Manana B, Sakr M, Zahreddine A, Tamim H, Bazarbachi A, et al. The impact of counseling on nutritional status among hematopoietic stem cell recipients: results of a randomized controlled trial. Bone Marrow Transpl. 2019;54:752–6. https://doi.org/10.1038/s41409-018-0366-3 .
doi: 10.1038/s41409-018-0366-3
Jabbour J, Manana B, Zahreddine A, Al-Shaar L, Bazarbachi A, Blaise D, et al. Vitamins and minerals intake adequacy in hematopoietic stem cell transplant: results of a randomized controlled trial. Bone Marrow Transpl. 2021;56:1106–15. https://doi.org/10.1038/s41409-020-01154-0 .
doi: 10.1038/s41409-020-01154-0
Mattsson J, Westin S, Edlund S, Remberger M. Poor oral nutrition after allogeneic stem cell transplantation correlates significantly with severe graft-versus-host disease. Bone Marrow Transpl. 2006;38:629–33. https://doi.org/10.1038/sj.bmt.1705493 .
doi: 10.1038/sj.bmt.1705493
Zama D, Gori D, Muratore E, Leardini D, Rallo F, Turroni S, et al. Enteral versus Parenteral Nutrition as Nutritional Support after Allogeneic Hematopoietic Stem Cell Transplantation: a Systematic Review and Meta-Analysis. Transpl Cell Ther. 2021;27:180.e1–180.e8. https://doi.org/10.1016/j.jtct.2020.11.006 .
doi: 10.1016/j.jtct.2020.11.006
Andersen S, Staudacher H, Weber N, Kennedy G, Varelias A, Banks M, et al. Pilot study investigating the effect of enteral and parenteral nutrition on the gastrointestinal microbiome post-allogeneic transplantation. Br J Haematol. 2020;188:570–81. https://doi.org/10.1111/bjh.16218 .
doi: 10.1111/bjh.16218
pubmed: 31612475
Baumgartner A, Hoskin K, Schuetz P. Optimization of nutrition during allogeneic hematologic stem cell transplantation. Curr Opin Clin Nutr Metab Care. 2018;21:152–8. https://doi.org/10.1097/MCO.0000000000000461 .
doi: 10.1097/MCO.0000000000000461
pubmed: 29465425
Botti S, van der Werf S, Stringer J, Eeltink C, Murray J, Ciceri F, et al. Nutritional support in stem cell transplantation programs: Results from a multicenter survey of nurses on behalf of the Nurses Group and Transplant Complications Working Party of the European Society for Blood and Marrow Transplantation and the Gruppo Italiano Trapianto di Midollo Osseo. Nutrition. 2020;79-80:110998. https://doi.org/10.1016/j.nut.2020.110998 .
doi: 10.1016/j.nut.2020.110998
pubmed: 32987334
Andersen S, Weber N, Kennedy G, Brown T, Banks M, Bauer J. Tolerability of proactive enteral nutrition post allogeneic haematopoietic progenitor cell transplant: a randomised comparison to standard care. Clin Nutr. 2020;39:1364–70. https://doi.org/10.1016/j.clnu.2019.06.012 .
doi: 10.1016/j.clnu.2019.06.012
pubmed: 31277913
Baumgartner A, Bargetzi M, Bargetzi A, Zueger N, Medinger M, Passweg J, et al. Nutritional support practices in hematopoietic stem cell transplantation centers: a nationwide comparison. Nutrition. 2017;35:43–50. https://doi.org/10.1016/j.nut.2016.10.007 .
doi: 10.1016/j.nut.2016.10.007
pubmed: 28241989
Pastore D, Bruno B, Carluccio P, De Candia MS, Mammoliti S, Borghero C, et al. Antiemetic prophylaxis in patients undergoing hematopoietic stem cell transplantation: a multicenter survey of the Gruppo Italiano Trapianto Midollo Osseo (GITMO) transplant programs. Ann Hematol. 2020;99:867–75. https://doi.org/10.1007/s00277-020-03945-3 .
doi: 10.1007/s00277-020-03945-3
pubmed: 32036421
Verdi Schumacher M, Moreira, Faulhaber GA. Nutritional status and hyperglycemia in the peritransplant period: a review of associations with parenteral nutrition and clinical outcomes. Rev Bras Hematol Hemoter. 2017;39:155–62. https://doi.org/10.1016/j.bjhh.2016.09.016 .
doi: 10.1016/j.bjhh.2016.09.016
pubmed: 28577653
pmcid: 5457457
Fuji S, Rovó A, Ohashi K, Griffith M, Einsele H, Kapp M, et al. How do I manage hyperglycemia/post-transplant diabetes mellitus after allogeneic HSCT. Bone Marrow Transpl. 2016;51:1041–9. https://doi.org/10.1038/bmt.2016.81 .
doi: 10.1038/bmt.2016.81
Seguy D, Duhamel A, Rejeb MB, Gomez E, Buhl ND, Bruno B, et al. Better outcome of patients undergoing enteral tube feeding after myeloablative conditioning for allogeneic stem cell transplantation. Transplantation 2012;94:287–94. https://doi.org/10.1097/TP.0b013e3182558f60 .
doi: 10.1097/TP.0b013e3182558f60
pubmed: 22785249
Gonzales F, Bruno B, Alarcón Fuentes M, De Berranger E, Guimber D, Behal H, et al. Better early outcome with enteral rather than parenteral nutrition in children undergoing MAC allo-SCT. Clin Nutr. 2018;37:2113–21. https://doi.org/10.1016/j.clnu.2017.10.005 .
doi: 10.1016/j.clnu.2017.10.005
pubmed: 29097037
van Dalen EC, Mank A, Leclercq E, Mulder RL, Davies M, Kersten MJ, et al. Low bacterial diet versus control diet to prevent infection in cancer patients treated with chemotherapy causing episodes of neutropenia. Cochrane Database Syst Rev. 2016;4:CD006247. https://doi.org/10.1002/14651858.CD006247.pub3 .
doi: 10.1002/14651858.CD006247.pub3
pubmed: 27107610
Lassiter M, Schneider SM. A pilot study comparing the neutropenic diet to a non-neutropenic diet in the allogeneic hematopoietic stem cell transplantation population. Clin J Oncol Nurs. 2015;19:273–8. https://doi.org/10.1188/15.CJON.19-03AP .
doi: 10.1188/15.CJON.19-03AP
pubmed: 26000578
Ball S, Brown TJ, Das A, Khera R, Khanna S, Gupta A. Effect of Neutropenic Diet on Infection Rates in Cancer Patients With Neutropenia: A Meta-analysis of Randomized Controlled Trials. Am J Clin Oncol. 2019;42:270–4. https://doi.org/10.1097/COC.0000000000000514 .
doi: 10.1097/COC.0000000000000514
pubmed: 30628912
Sonbol MB, Jain T, Firwana B, Hilal T, Deleon T, Murad A, et al. Neutropenic diets to prevent cancer infections: updated systematic review and meta-analysis. BMJ Support. Palliat Care. 2019;9:425–33. https://doi.org/10.1136/bmjspcare-2018-001742 .
doi: 10.1136/bmjspcare-2018-001742
Moody KM, Baker RA, Santizo RO, Olmez I, Spies JM, Buthmann A, et al. A randomized trial of the effectiveness of the neutropenic diet versus food safety guidelines on infection rate in pediatric oncology patients. Pediatr Blood Cancer. 2018;65. https://doi.org/10.1002/pbc.26711 .
Taggart C, Neumann N, Alonso PB, Lane A, Pate A, Stegman A, et al. Comparing a neutropenic diet to a food safety-based diet in pediatric patients undergoing hematopoietic stem cell transplantation. Biol Blood Marrow Transpl. 2019;25:1382–6. https://doi.org/10.1016/j.bbmt.2019.03.017 .
doi: 10.1016/j.bbmt.2019.03.017
Ramamoorthy V, Rubens M, Appunni S, Saxena A, McGranaghan P, Veledar E, et al. Lack of efficacy of the neutropenic diet in decreasing infections among cancer patients: a systematic review. Nutr Cancer. 2020;72:1125–34. https://doi.org/10.1080/01635581.2019.1675723 .
doi: 10.1080/01635581.2019.1675723
pubmed: 31608705
Ma Y, Lu X, Liu H. Neutropenic diet cannot reduce the risk of infection and mortality in oncology patients with neutropenia. Front Oncol. 2022;12:836371. https://doi.org/10.3389/fonc.2022.836371 .
doi: 10.3389/fonc.2022.836371
pubmed: 35356218
pmcid: 8959862
Baumgartner A, Schuetz P. Nutritional Support. In: Carreras E, Dufour C, Mohty M, Kröger N, editors. The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies. 7th ed. Cham (CH): Springer; 2019. Chapter 24.
Kenyon M, Babic A, editors. The European Blood and Marrow Transplantation Textbook for Nurses: Under the Auspices of EBMT [Internet]. Cham (CH): Springer; 2018.
Brown TJ, Mukhija D, Premnath N, Venkatraman A, Jiv Singh Nagpal S, Gupta A. Dissemination of Information on Neutropenic Diet by Top US Cancer Centers: In-line with the Evidence? Nutr Cancer. 2019;71:1272–5. https://doi.org/10.1080/01635581.2019.1606262 .
doi: 10.1080/01635581.2019.1606262
pubmed: 31045449
Toenges R, Greinix H, Lawitschka A, Halter J, Baumgartner A, Simon A, et al. Current practice in nutrition after allogeneic hematopoietic stem cell transplantation—Results from a survey among hematopoietic stem cell transplant centers. Clin Nutr. 2021;40:1571–7. https://doi.org/10.1016/j.clnu.2021.02.030 .
doi: 10.1016/j.clnu.2021.02.030
pubmed: 33744601
Radhakrishnan V, Lagudu PBB, Gangopadhyay D, Vijaykumar V, Rajaraman S, Perumal Kalaiyarasi J, et al. Neutropenic versus regular diet for acute leukaemia induction chemotherapy: randomised controlled trial. BMJ Support Palliat Care. 2022;12:421–30. https://doi.org/10.1136/spcare-2022-003833 .
doi: 10.1136/spcare-2022-003833
pubmed: 35803707
World Health Organization, https://trialsearch.who.int/Trial2.aspx?TrialID=IRCT20220208053971N1 .
Gupta A, Gupta AK, Meena JP, Khan MA, Agarwala A, Seth R. A Pilot Randomised Controlled Trial Examining the Benefit of a Neutropenic Diet for Children Undergoing Cancer Treatment. Nutr Cancer. 2022;74:2930–6. https://doi.org/10.1080/01635581.2022.2044060 .
doi: 10.1080/01635581.2022.2044060
pubmed: 35225115
French MR, Levy-Milne R, Zibrik D. A survey of the use of low microbial diets in pediatric bone marrow transplant programs. J Am Diet Assoc. 2001;101:1194–8. https://doi.org/10.1016/S0002-8223(01)00292-9 .
doi: 10.1016/S0002-8223(01)00292-9
pubmed: 11678491
Fuji S, Mori T, Lee V, Cheng J, Linton N, Lie A, et al. A multicenter international survey related to the nutritional support after hematopoietic stem cell transplantation endorsed by the ASIA Pacific Blood and Marrow Transplantation (APBMT). Food Nutr Sci. 2012;3:417–9.
Baumgartner A, Bargetzi A, Zueger N, Bargetzi M, Medinger M, Bounoure L, et al. Revisiting nutritional support for allogeneic hematologic stem cell transplantation-a systematic review. Bone Marrow Transpl. 2017;52:506–13. https://doi.org/10.1038/bmt.2016.310 .
doi: 10.1038/bmt.2016.310
Botti S, Liptrott SJ, Gargiulo G, Orlando L. Nutritional support in patients undergoing haematopoietic stem cell transplantation: a multicentre survey of the Gruppo Italiano Trapianto Midollo Osseo (GITMO) transplant programmes. Ecancermedicalscience. 2015;9:545. https://doi.org/10.3332/ecancer.2015.545 .
doi: 10.3332/ecancer.2015.545
pubmed: 26180544
pmcid: 4494819
Calder PC. Immunonutrition in surgical and critically ill patients. Br J Nutr. 2007;98:S133–S139. https://doi.org/10.1017/S0007114507832909 .
doi: 10.1017/S0007114507832909
pubmed: 17922951
Kota H, Chamberlain RS. Immunonutrition is associated with a decreased incidence of graft-versus-host disease in bone marrow transplant recipients: a meta-analysis. JPEN J Parenter Enter Nutr. 2017;41:1286–92. https://doi.org/10.1177/0148607116663278 .
doi: 10.1177/0148607116663278
Andermann TM, Rezvani A, Bhatt AS. Microbiota manipulation with prebiotics and probiotics in patients undergoing stem cell transplantation. Curr Hematol Malig Rep. 2016;11:19–28. https://doi.org/10.1007/s11899-016-0302-9 .
doi: 10.1007/s11899-016-0302-9
pubmed: 26780719
pmcid: 4996265
Morishita S, Kaida K, Tanaka T, Itani Y, Ikegame K, Okada M, et al. Prevalence of sarcopenia and relevance of body composition, physiological function, fatigue, and health-related quality of life in patients before allogeneic hematopoietic stem cell transplantation. Support Care Cancer. 2012;20:3161–8. https://doi.org/10.1007/s00520-012-1460-5 .
doi: 10.1007/s00520-012-1460-5
pubmed: 22526152
Stene GB, Helbostad JL, Balstad TR, Riphagen II, Kaasa S, Oldervoll LM. Effect of physical exercise on muscle mass and strength in cancer patients during treatment-a systematic review. Crit Rev Oncol Hematol. 2013;88:573–93. https://doi.org/10.1016/j.critrevonc.2013.07.001 .
doi: 10.1016/j.critrevonc.2013.07.001
pubmed: 23932804
Wiskemann J, Kleindienst N, Kuehl R, Dreger P, Schwerdtfeger R, Bohus M. Effects of physical exercise on survival after allogeneic stem cell transplantation. Int J Cancer. 2015;137:2749–56. https://doi.org/10.1002/ijc.29633 .
doi: 10.1002/ijc.29633
pubmed: 26061092
Cuvelier S, Blaise D, Boher JM, Villaron-Goetgheluck C, Justafré S, Pakradouni J, et al. A study of elite sport-inspired coaching for patients after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transpl. 2021;56:2755–62. https://doi.org/10.1038/s41409-021-01401-y .
doi: 10.1038/s41409-021-01401-y
Blaise D, Calvin S, Cuvelier S, Ben Soussan P, Villaron C, Dantin P, et al. REBOUND “Trained to live again”: The practice of great Olympic coaches improves and enhances the quality of life of cancer patients in remission after hematopoietic stem cell allogeneic transplantation. Bone Marrow Transpl. 2020;55:997–9. https://doi.org/10.1038/s41409-020-0845-1 .
doi: 10.1038/s41409-020-0845-1
Oudin C, Berbis J, Bertrand Y, Vercasson C, Thomas F, Chastagner P, et al. Prevalence and characteristics of metabolic syndrome in adults from the French childhood leukemia survivors’ cohort: a comparison with controls from the French population. Haematologica. 2018;103:645–54. https://doi.org/10.3324/haematol.2017.176123 .
doi: 10.3324/haematol.2017.176123
pubmed: 29351982
pmcid: 5865433
White M, Murphy AJ, Hallahan A, Ware RS, Fraser C, Davies PS. Survival in overweight and underweight children undergoing hematopoietic stem cell transplantation. Eur J Clin Nutr. 2012;66:1120–3. https://doi.org/10.1038/ejcn.2012.109 .
doi: 10.1038/ejcn.2012.109
pubmed: 22892438
Gebauer J, Higham C, Langer T, Denzer C, Brabant G. Long-Term Endocrine and Metabolic Consequences of Cancer Treatment: A Systematic Review. Endocr Rev. 2019;40:711–67. https://doi.org/10.1210/er.2018-00092 .
doi: 10.1210/er.2018-00092
pubmed: 30476004
Diesch-Furlanetto T, Gabriel M, Zajac-Spychala O, Cattoni A, Hoeben BAW, Balduzzi A. Late Effects After Haematopoietic Stem Cell Transplantation in ALL, Long-Term Follow-Up and Transition: A Step Into Adult Life. Front Pediatr. 2021;9:773895. https://doi.org/10.3389/fped.2021.773895 .
doi: 10.3389/fped.2021.773895
pubmed: 34900873
pmcid: 8652149