Secondary post-oncologic vulvar reconstruction - a simplified algorithm.

flap reconstruction groin reconstruction gynecological cancer secondary vulvar reconstruction vulvar cancer vulvar reconstruction vulvoperineal reconstruction

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2023
Historique:
received: 28 03 2023
accepted: 16 05 2023
medline: 6 7 2023
pubmed: 6 7 2023
entrez: 6 7 2023
Statut: epublish

Résumé

Surgical treatment is the gold standard of care for vulvar cancer and is burdened by a high risk of wound complications due to the poor healing typical of the female genital area. Moreover, this malignancy has a high risk of local relapse even after wide excision. For these reasons, secondary reconstruction of the vulvoperineal area is a relevant and challenging scenario for gynecologists and plastic surgeons. The presence of tissue already operated on and undermined, scars, incisions, the possibility of previous radiation therapy, contamination of urinary and fecal pathogens in the dehiscent wound or ulcerated tumor, and the unavailability of some flaps employed during the primary procedure are typical complexities of this surgery. Due to the rarity of this tumor, a rational approach to secondary reconstruction has never been proposed in the literature. In this observational retrospective study, we reviewed the clinical data of patients affected by vulvar cancer who underwent secondary reconstruction of the vulvoperineal area in our hospital between 2013 and 2023. Oncological, reconstructive, demographic, and complication data were recorded. The primary outcome measure was the incidence of wound complications. The secondary outcome measure was the indication of the different flaps, according to the defect, to establish an algorithm for decision-making. Sixty-six patients were included; mean age was 71.3 ± 9.4 years, and the mean BMI was 25.1 ± 4.9. The mean size of the defect repaired by secondary vulvar reconstruction was 178 cm A systematic approach to secondary vulvar reconstruction can provide good surgical results with a low rate of complications. The geometry of the defect and the use of both traditional and perforator flaps should guide the choice of the reconstructive technique.

Identifiants

pubmed: 37409264
doi: 10.3389/fonc.2023.1195580
pmc: PMC10318400
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1195580

Informations de copyright

Copyright © 2023 Caretto, Servillo, Tagliaferri, Lancellotta, Fragomeni, Garganese, Scambia and Gentileschi.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Anna Amelia Caretto (AA)

Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Rome, Italy.

Maria Servillo (M)

Casa di Cura Villa Stuart, BAC Center, Rome, Italy.

Luca Tagliaferri (L)

Fondazione Policlinico Universitario A. Gemelli IRCCS, Dipartimento Diagnostica per Immagini Radioterapia Oncologica ed Ematologia, Rome, Italy.

Valentina Lancellotta (V)

Fondazione Policlinico Universitario A. Gemelli IRCCS, Dipartimento Diagnostica per Immagini Radioterapia Oncologica ed Ematologia, Rome, Italy.

Simona Maria Fragomeni (SM)

Fondazione Policlinico Universitario A. Gemelli IRCCS, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Ginecologia Oncologica, Rome, Italy.

Giorgia Garganese (G)

Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Rome, Italy.
Fondazione Policlinico Universitario A. Gemelli IRCCS, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Ginecologia Oncologica, Rome, Italy.

Giovanni Scambia (G)

Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Rome, Italy.
Fondazione Policlinico Universitario A. Gemelli IRCCS, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Ginecologia Oncologica, Rome, Italy.

Stefano Gentileschi (S)

Dipartimento Universitario di Medicina e Chirurgia Traslazionale, Rome, Italy.
Fondazione Policlinico Universitario A. Gemelli IRCCS, Dipartimento Scienze Della Salute Della Donna E Del Bambino E Di Sanità Pubblica, Unità di Chirurgia Plastica, Rome, Italy.

Classifications MeSH