Parenchymal volume analysis to assess longitudinal functional decline following partial nephrectomy.


Journal

BJU international
ISSN: 1464-410X
Titre abrégé: BJU Int
Pays: England
ID NLM: 100886721

Informations de publication

Date de publication:
10 2023
Historique:
medline: 22 9 2023
pubmed: 6 7 2023
entrez: 6 7 2023
Statut: ppublish

Résumé

To identify factors associated with longitudinal ipsilateral functional decline after partial nephrectomy (PN). Of 1140 patients managed with PN (2012-2014), 349 (31%) had imaging/serum creatinine levels pre-PN, 1-12 months post-PN (new baseline), and >3 years later necessary for inclusion. Parenchymal-volume analysis was used to determine split renal function. Patients were grouped as having significant renal comorbidity (Cohort The median follow-up was 6.3 years with 87/226/36 patients having cold/warm/zero ischaemia. The median cold/warm ischaemia times were 32/22 min. Overall, the median tumour size was 3.0 cm. The preoperative glomerular filtration rate (GFR) and new baseline GFR (NBGFR) were 81 and 71 mL/min/1.73 m Longitudinal renal function following PN generally follows the normal ageing process. Significant renal comorbidities, age, warm ischaemia, and ipsilateral parenchymal atrophy were the most important predictors of ipsilateral functional decline following establishment of NBGFR.

Identifiants

pubmed: 37409822
doi: 10.1111/bju.16110
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

435-443

Informations de copyright

© 2023 The Authors. BJU International published by John Wiley & Sons Ltd on behalf of BJU International.

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Auteurs

Carlos Munoz-Lopez (C)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Kieran Lewis (K)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Worapat Attawettayanon (W)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Division of Urology, Department of Surgery, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, Thailand.

Yosuke Yasuda (Y)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Tokyo Medical and Dental University, Graduate School, Tokyo, Japan.

João Pedro Emrich Accioly (JPE)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Nityam Rathi (N)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Zaeem Lone (Z)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Melissa Boumitri (M)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Rebecca A Campbell (RA)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Andrew Wood (A)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Jihad Kaouk (J)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Georges-Pascal Haber (GP)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Mohamad Eltemamy (M)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Venkatesh Krishnamurthi (V)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Robert Abouassaly (R)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Samuel Haywood (S)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Christopher Weight (C)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Steven C Campbell (SC)

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

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