Use of Antimicrobial Irrigation and Incidence of Capsular Contracture in Breast Augmentation and Immediate Implant-Based Breast Reconstruction.

Breast implant Breast reconstruction Capsular contracture Surgical site infections Topical antibiotics

Journal

Aesthetic plastic surgery
ISSN: 1432-5241
Titre abrégé: Aesthetic Plast Surg
Pays: United States
ID NLM: 7701756

Informations de publication

Date de publication:
06 Jul 2023
Historique:
received: 25 04 2023
accepted: 04 06 2023
medline: 6 7 2023
pubmed: 6 7 2023
entrez: 6 7 2023
Statut: aheadofprint

Résumé

Capsular contracture (CC) is one of the most common complications of implant-based breast reconstruction or augmentation surgery. Common risk factors of CC include biofilm, surgical site infections, history of prior CC or fibrosis, history of radiation therapy, and implant characteristics. Though bacterial contamination of breast protheses is associated with adverse sequelae, there are not universally accepted guidelines and limited best practice recommendations for antimicrobial breast pocket irrigation. Despite advanced molecular biology, the exact mechanism of this complication is not fully understood. Interventions that decrease the rate of CC include antibiotic prophylaxis or irrigation, acellular dermal matrix, leukotriene inhibitors, surgical techniques, and others. However, there is inconsistent evidence supporting these risk factors, and the current data was based on broad heterogeneous studies. The objective of this review was to provide a summary of the current data of contributing risk factors as well as preventative and treatment measures for CC.Level of Evidence III This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors http://www.springer.com/00266.

Identifiants

pubmed: 37410129
doi: 10.1007/s00266-023-03453-5
pii: 10.1007/s00266-023-03453-5
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023. The Author(s).

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Auteurs

Giuzio Federica (G)

Department of Sciences, University of Basilicata, Potenza, Italy.
Spinoff TNcKILLERS s.r.l, Ateneo Lucano street 10, 85100, Potenza, Italy.
U.O.C. Primary Care and Territorial Health, Social and Health Department, State Hospital, Falciano, Republic of San Marino.

Fabrizio Tommaso (F)

Department of Plastic Surgery, IRCCS, Referral Cancer Center of Basilicata, Rionero in Vulture, PZ, Italy.

Catalano Alessia (C)

Department of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", Bari, Italy.

Ceccarini Agostino (C)

U.O.C. Primary Care and Territorial Health, Social and Health Department, State Hospital, Falciano, Republic of San Marino.

Bodog Florian (B)

Department of Surgery, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.

Giuliani Antonio (G)

U.O.C. of General and Emergency Surgery A.O.R. "San Carlo", Potenza, Basilicata, Italy.

Massariello Domenico Nicola (M)

U.O.S.D of Plastic Surgery A.O.R "San Carlo", Potenza, Italy.

Raweh Abdallah (R)

Cardiac Surgery Department, Yas Clinic, Abu Dhabi, United Arab Emirates.

Saturnino Carmela (S)

Department of Sciences, University of Basilicata, Potenza, Italy.

Svolacchia Lorenzo (S)

Departments of Medical-Surgical Sciences and Biotechnologies, La Sapienza University, Rome, Italy.

Brongo Sergio (B)

Department of Plastic Surgery, University of Salerno, Campania, Italy. sergiobrongo@gmail.com.

Classifications MeSH