The ubiquitin-protein ligase MIEL1 localizes to peroxisomes to promote seedling oleosin degradation and lipid droplet mobilization.
Arabidopsis thaliana
E3 ubiquitin ligase
PIRH2
lipid droplet
peroxisome
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
18 Jul 2023
18 Jul 2023
Historique:
medline:
10
7
2023
pubmed:
6
7
2023
entrez:
6
7
2023
Statut:
ppublish
Résumé
Lipid droplets are organelles conserved across eukaryotes that store and release neutral lipids to regulate energy homeostasis. In oilseed plants, fats stored in seed lipid droplets provide fixed carbon for seedling growth before photosynthesis begins. As fatty acids released from lipid droplet triacylglycerol are catabolized in peroxisomes, lipid droplet coat proteins are ubiquitinated, extracted, and degraded. In
Identifiants
pubmed: 37410814
doi: 10.1073/pnas.2304870120
pmc: PMC10629534
doi:
Substances chimiques
Arabidopsis Proteins
0
MYB30 protein, Arabidopsis
0
Transcription Factors
0
Tumor Suppressor Protein p53
0
Ubiquitin-Protein Ligases
EC 2.3.2.27
MIEL1 protein, Arabidopsis
EC 2.3.2.27
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2304870120Subventions
Organisme : NCI NIH HHS
ID : P30 CA091842
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM129325
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM130338
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002345
Pays : United States
Références
J Biol Chem. 2008 May 23;283(21):14190-7
pubmed: 18359941
Proteomics. 2009 Jun;9(12):3268-84
pubmed: 19562800
Plants (Basel). 2021 Mar 09;10(3):
pubmed: 33803467
J Biol Chem. 2005 Dec 30;280(52):42841-7
pubmed: 16115879
Plant Physiol. 2001 Nov;127(3):1266-78
pubmed: 11706205
Curr Opin Plant Biol. 2016 Dec;34:17-26
pubmed: 27500947
Plant Physiol. 1990 Nov;94(3):1282-9
pubmed: 16667830
Front Plant Sci. 2019 Feb 13;10:98
pubmed: 30815004
PLoS Genet. 2011 Nov;7(11):e1002360
pubmed: 22125490
EMBO Mol Med. 2013 Jul;5(7):973-83
pubmed: 23740690
Biochimie. 2016 Jan;120:17-27
pubmed: 26187474
Metallomics. 2017 Jul 19;9(7):876-890
pubmed: 28620661
Plant Cell. 2010 Jul;22(7):2219-36
pubmed: 20675571
Plant Physiol. 2015 Sep;169(1):453-70
pubmed: 26232488
Nat Commun. 2020 Dec 4;11(1):6221
pubmed: 33277488
J Mol Biol. 2018 Jul 20;430(15):2237-2243
pubmed: 29258817
Plant Cell. 2015 Nov;27(11):3228-44
pubmed: 26508764
Annu Rev Plant Biol. 2023 May 22;74:195-223
pubmed: 36413579
Plant Physiol. 2014 Apr;164(4):1866-78
pubmed: 24515832
Plant Cell. 1997 Oct;9(10):1781-90
pubmed: 9368415
Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3077-82
pubmed: 12629214
Plant Cell Physiol. 2015 Jul;56(7):1374-87
pubmed: 25907570
Biochim Biophys Acta. 2006 Jan;1761(1):83-90
pubmed: 16448845
PLoS One. 2018 Aug 31;13(8):e0203442
pubmed: 30169501
Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt B):1221-1232
pubmed: 28754637
Mol Cell. 2022 Sep 1;82(17):3209-3225.e7
pubmed: 35931083
Plant Cell Physiol. 2012 Jul;53(7):1310-21
pubmed: 22611176
Plant Physiol Biochem. 2004 Jun;42(6):501-9
pubmed: 15246063
Nat Commun. 2021 Sep 22;12(1):5598
pubmed: 34552075
Plant Cell. 2005 Dec;17(12):3422-35
pubmed: 16272432
New Phytol. 2021 May;230(3):1095-1109
pubmed: 33492673
Plant Physiol. 2005 Jan;137(1):13-30
pubmed: 15644464
Essays Biochem. 2022 Aug 5;66(2):229-242
pubmed: 35538741
J Cell Biol. 1999 Jul 12;146(1):99-112
pubmed: 10402463
Mol Cell Proteomics. 2008 Oct;7(10):2019-27
pubmed: 18669619
Plant Biotechnol J. 2017 Jul;15(7):824-836
pubmed: 27987528
Nat Commun. 2016 Sep 12;7:12525
pubmed: 27615387
Mol Plant. 2011 May;4(3):477-86
pubmed: 21357648
Plant Cell. 2013 Sep;25(9):3506-18
pubmed: 24076979
Plant Physiol. 2015 Jan;167(1):273-86
pubmed: 25452667
Nat Struct Mol Biol. 2008 Dec;15(12):1334-42
pubmed: 19043414
Nat Commun. 2013;4:1476
pubmed: 23403577
Prog Lipid Res. 2020 Apr;78:101029
pubmed: 32348789
Science. 2022 Dec 16;378(6625):eadf3971
pubmed: 36520918
Science. 2003 Aug 1;301(5633):653-7
pubmed: 12893945
Plant Physiol. 2018 Jan;176(1):162-177
pubmed: 29021223
Plant Physiol. 2016 Nov;172(3):1643-1656
pubmed: 27650450
Nature. 2021 Aug;596(7873):583-589
pubmed: 34265844
Plant Cell. 1998 Feb;10(2):183-95
pubmed: 9490742
Nucleic Acids Res. 2022 Jan 7;50(D1):D439-D444
pubmed: 34791371
Nat Rev Gastroenterol Hepatol. 2017 Jun;14(6):343-355
pubmed: 28428634
Curr Biol. 2016 Mar 7;26(5):707-12
pubmed: 26898465
Plant Cell. 2018 Sep;30(9):2137-2160
pubmed: 30087207
Semin Cell Dev Biol. 2020 Dec;108:82-93
pubmed: 32147380
EMBO J. 2002 Jun 17;21(12):2912-22
pubmed: 12065405
Plant J. 2008 Sep;55(5):798-809
pubmed: 18485063
Plant Physiol. 2018 Mar;176(3):1894-1918
pubmed: 29269574
Annu Rev Biochem. 2009;78:399-434
pubmed: 19489725
J Biol Chem. 2016 Sep 16;291(38):19734-45
pubmed: 27466365
Nat Commun. 2013;4:2792
pubmed: 24253678
J Integr Plant Biol. 2023 Feb;65(2):371-380
pubmed: 35975710
Plant J. 2010 Feb 1;61(3):519-28
pubmed: 19891705
Nat Cell Biol. 2015 Jun;17(6):759-70
pubmed: 25961502
Nature. 2022 Jul;607(7918):374-380
pubmed: 35768507
Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4561-6
pubmed: 19246395
Adv Exp Med Biol. 2020;1299:3-17
pubmed: 33417203
Cell. 2003 Mar 21;112(6):779-91
pubmed: 12654245
Mol Biol Cell. 2018 Feb 15;29(4):396-407
pubmed: 29282281
Plant Cell. 2006 Aug;18(8):1961-74
pubmed: 16877495
Cells. 2022 Apr 30;11(9):
pubmed: 35563824
Plant Cell. 2022 Oct 27;34(11):4255-4273
pubmed: 35775937
Plant Cell Environ. 2018 Oct;41(10):2463-2474
pubmed: 29878379
Plant Cell. 2018 Sep;30(9):2116-2136
pubmed: 30087208
Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10179-84
pubmed: 12119395
Nat Methods. 2009 May;6(5):343-5
pubmed: 19363495
Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4158-63
pubmed: 25775518
BMC Res Notes. 2015 Mar 03;8:63
pubmed: 25884475
Genetics. 2000 Nov;156(3):1323-37
pubmed: 11063705
Front Cell Dev Biol. 2022 Feb 18;10:838923
pubmed: 35300425
Plant Cell. 2019 Jul;31(7):1598-1613
pubmed: 31036588
Nat Methods. 2013 May;10(5):407-9
pubmed: 23524392
Plant Cell. 2006 Mar;18(3):665-75
pubmed: 16473965