A patient with secondary syphilis following incomplete treatment of primary infection.


Journal

The Lancet. Infectious diseases
ISSN: 1474-4457
Titre abrégé: Lancet Infect Dis
Pays: United States
ID NLM: 101130150

Informations de publication

Date de publication:
11 2023
Historique:
received: 31 10 2022
revised: 06 03 2023
accepted: 24 03 2023
medline: 30 10 2023
pubmed: 7 7 2023
entrez: 6 7 2023
Statut: ppublish

Résumé

Syphilis is a bacterial infection caused by Treponema pallidum and is primarily transmitted via skin-to-skin or mucosal contact during sexual encounters, or through vertical transmission during pregnancy. Cases continue to rise globally across various demographic groups despite effective treatment and prevention interventions. We discuss the case of a 28-year-old cisgender man who presented with secondary syphilis 1 month after being inadequately treated for primary syphilis. Individuals can present with symptoms and signs of syphilis to clinicians of various subspecialties due to diverse clinical presentation. All health-care providers should be able to identify the common and less common manifestations of this infection, and adequate treatment and follow-up are crucial to preventing serious sequelae. Novel biomedical prevention interventions, such as doxycycline post-exposure prophylaxis, are on the horizon.

Identifiants

pubmed: 37414065
pii: S1473-3099(23)00211-6
doi: 10.1016/S1473-3099(23)00211-6
pii:
doi:

Substances chimiques

Doxycycline N12000U13O

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e497-e504

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests We declare no competing interests.

Auteurs

Zachary Lorenz (Z)

Division of General Internal Medicine, Johns Hopkins University School of Medicine, Bayview Medical Center, Baltimore, MD, USA.

Lauren Rybolt (L)

Department of Internal Medicine, Division of General Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

Khalil G Ghanem (KG)

Department of Internal Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Bayview Medical Center, Baltimore, MD, USA.

Jennifer Shiroky-Kochavi (J)

Department of Internal Medicine, Division of General Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, USA. Electronic address: jshirokykochavi@usf.edu.

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Classifications MeSH