Diagnostic Performance and Safety of Positron Emission Tomography with

Male Humans Positron Emission Tomography Computed Tomography / methods Prospective Studies Positron-Emission Tomography Prostatic Neoplasms / diagnostic imaging Prostate / pathology Gallium Radioisotopes
Positron emission tomography Prostate-specific membrane antigen Prostatic neoplasms Radiohybrid prostate-specific membrane antigen

Journal

European urology
ISSN: 1873-7560
Titre abrégé: Eur Urol
Pays: Switzerland
ID NLM: 7512719

Informations de publication

Date de publication:
10 2023
Historique:
received: 13 02 2023
revised: 20 05 2023
accepted: 20 06 2023
medline: 18 9 2023
pubmed: 7 7 2023
entrez: 6 7 2023
Statut: ppublish

Résumé

Radiohybrid (rh) To evaluate the diagnostic performance and safety of Data on Patients underwent positron emission tomography/computed tomography (PET/CT) 50-70 min after an injection of 296 MBq Of 372 patients screened, 352 had evaluable Across all risk stratifications, In order to select the most appropriate treatment for patients with prostate cancer, it is critical to diagnose the disease burden accurately at initial diagnosis. In this study, we investigated a new diagnostic imaging agent in a large population of men with primary prostate cancer. We found it to have an excellent safety profile and to provide clinically useful information regarding the presence of disease beyond the prostate.

Sections du résumé

BACKGROUND
Radiohybrid (rh)
OBJECTIVE
To evaluate the diagnostic performance and safety of
DESIGN, SETTING, AND PARTICIPANTS
Data on
OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS
Patients underwent positron emission tomography/computed tomography (PET/CT) 50-70 min after an injection of 296 MBq
RESULTS AND LIMITATIONS
Of 372 patients screened, 352 had evaluable
CONCLUSIONS
Across all risk stratifications,
PATIENT SUMMARY
In order to select the most appropriate treatment for patients with prostate cancer, it is critical to diagnose the disease burden accurately at initial diagnosis. In this study, we investigated a new diagnostic imaging agent in a large population of men with primary prostate cancer. We found it to have an excellent safety profile and to provide clinically useful information regarding the presence of disease beyond the prostate.

Identifiants

DOI: 10.1016/j.eururo.2023.06.018 PMID: 37414702
pubmed: 37414702
pii: S0302-2838(23)02949-4
doi: 10.1016/j.eururo.2023.06.018
pii:
doi:

Substances chimiques

Gallium Radioisotopes 0

Banques de données

ClinicalTrials.gov
['NCT04186819']

Types de publication

Multicenter Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

361-370

Investigateurs

Mohamad Allaf (M)
Gerald Andriole (G)
Ryan J Avery (RJ)
Norbert Avril (N)
Helen Barker (H)
Laurence Belkoff (L)
Lars Budäus (L)
Michael L Cher (ML)
Diane Chisholm (D)
Matthew F Covington (MF)
Ian Cox (I)
Michael Ferrandino (M)
Mark T Fleming (MT)
Dinko Franceschi (D)
Peter Gardiner (P)
Benjamin Gartrell (B)
David Gauden (D)
Ergela Hasa (E)
Rick Hermsen (R)
Thomas Horn (T)
Pooya Iranpour (P)
Heather Jacene (H)
Isuru Jayaratna (I)
Shreyas S Joshi (SS)
Matthew Kay (M)
Lale Kostakoglu (L)
Phillip Kuo (P)
William Lavely (W)
Mary Lokuta (M)
Benjamin Lowentritt (B)
Matthew P Miller (MP)
Jeffrey W Nix (JW)
Kenneth Ogan (K)
Ross Penny (R)
Morand Piert (M)
Andrei Purysko (A)
Gregory Ravizzini (G)
Daniel Saltzstein (D)
Bital Savir-Baruch (B)
Barry A Siegel (BA)
Thomas Steuber (T)
Przemyslaw Twardowski (P)
Edward Uchio (E)
Gary A Ulaner (GA)
Jenna M Wixom (JM)
Don Yoo (D)
Katherine Zukotynski (K)

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2023. Published by Elsevier B.V.

Auteurs

Devaki Shilpa Surasi (DS)

Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: dssurasi@mdanderson.org.

Matthias Eiber (M)

Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Tobias Maurer (T)

Martini-Klinik, Hamburg, Germany; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

Mark A Preston (MA)

Brigham and Women's Hospital, Boston, MA, USA.

Brian T Helfand (BT)

NorthShore University HealthSystem, Evanston, IL, USA.

David Josephson (D)

Tower Urology, Los Angeles, CA, USA; Cedars Sinai Medical Center, Los Angeles, CA, USA.

Ashutosh K Tewari (AK)

Mount Sinai Hospital, New York, NY, USA.

Diederik M Somford (DM)

Department of Urology, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands; Prosper Prostate Cancer Clinics, Nijmegen/Eindhoven, The Netherlands.

Soroush Rais-Bahrami (S)

Department of Urology, University of Alabama at Birmingham, Birmingham, AL, USA.

Bridget F Koontz (BF)

Duke University School of Medicine, Durham, NC, USA.

Peter J Bostrom (PJ)

Turku University Central Hospital, Turku, Finland; University of Turku, Turku, Finland.

Albert Chau (A)

Blue Earth Diagnostics Ltd, Oxford, UK.

Phillip Davis (P)

Blue Earth Diagnostics Inc, Monroe Township, NJ, USA.

David M Schuster (DM)

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA.

Brian F Chapin (BF)

Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Diagnostic Performance and Safety of Positron...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Tomographie par émission de positons couplée à la tomodensitométrie › Diagnostic Performance and Safety of Positron...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Diagnostic Performance and Safety of Positron...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Diagnostic Performance and Safety of Positron...
questionsmedicales.fr › Maladies urogénitales › Tumeurs de l'appareil urogénital › Tumeurs de l'appareil génital mâle › Tumeurs de la prostate › Diagnostic Performance and Safety of Positron...
questionsmedicales.fr › Tissus › Glandes exocrines › Prostate › Diagnostic Performance and Safety of Positron...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Gallium › Isotopes du gallium › Radio-isotopes du gallium › Diagnostic Performance and Safety of Positron...