A Multicenter Study of Genotype Variation/Demographic Patterns in 2475 Individuals Including 1444 Cases With Breast Cancer in Turkey.

BRCA1 BRCA2 Breast cancer genomic profiling population study

Journal

European journal of breast health
ISSN: 2587-0831
Titre abrégé: Eur J Breast Health
Pays: Turkey
ID NLM: 101709357

Informations de publication

Date de publication:
Jul 2023
Historique:
received: 29 03 2023
accepted: 30 05 2023
medline: 7 7 2023
pubmed: 7 7 2023
entrez: 7 7 2023
Statut: epublish

Résumé

Breast cancer (BC) is the most common cancer type in women and may be inherited, mostly in an autosomal dominant pattern. The clinical diagnosis of BC relies on the published diagnostic criteria, and analysis of two genes, Mutational analyses for the Overall, mutations were identified in 17% (421/2475), while the percentage of mutation carriers in cases of BC was similar, 16.6% (239/1444). Patients with

Identifiants

pubmed: 37415649
doi: 10.4274/ejbh.galenos.2023.2023-2-5
pii: 60750
pmc: PMC10320635
doi:

Types de publication

Journal Article

Langues

eng

Pagination

235-252

Informations de copyright

©Copyright 2023 by the the Turkish Federation of Breast Diseases Societies / European Journal of Breast Health published by Galenos Publishing House.

Déclaration de conflit d'intérêts

Conflict of Interest: No conflict of interest was declared by the authors.

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Auteurs

Ibrahim Boga (I)

Cukurova University AGENTEM (Adana Genetic Diseases Diagnosis and Treatment Center), Adana, Turkey.
Department of Medical Genetics, Cukurova University Faculty of Medicine, Adana, Turkey.

Sebnem Ozemri Sag (S)

Department of Medical Genetics and Genetic Diseases Diagnosis Center, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Nilgun Duman (N)

Department of Medical Genetics, Bezmialem Vakif University, Dragos Hospital, Istanbul, Turkey.

Sevda Yesim Ozdemir (SY)

Department of Medical Genetics, Uskudar University Faculty of Medicine, Istanbul, Turkey.

Mahmut Cerkez Ergoren (MC)

Department of Medical Genetics, Near East University Faculty of Medicine, Nicosia, Cyprus.
Near East University, DESAM Institute, Nicosia, Cyprus.

Kubilay Dalci (K)

Department of General Surgery, Cukurova University Faculty of Medicine, Adana, Turkey.

Cem Mujde (C)

Cukurova University AGENTEM (Adana Genetic Diseases Diagnosis and Treatment Center), Adana, Turkey.

Cem Kaan Parsak (CK)

Department of General Surgery, Cukurova University Faculty of Medicine, Adana, Turkey.

Cagla Rencuzogullari (C)

Cukurova University AGENTEM (Adana Genetic Diseases Diagnosis and Treatment Center), Adana, Turkey.

Ozge Sonmezler (O)

Cukurova University AGENTEM (Adana Genetic Diseases Diagnosis and Treatment Center), Adana, Turkey.

Orcun Yalav (O)

Department of General Surgery, Cukurova University Faculty of Medicine, Adana, Turkey.

Adem Alemdar (A)

Department of Translational Medicine, Bursa Uludag University Institute of Health Sciences, Bursa, Turkey.

Lamiya Aliyeva (L)

Department of Medical Genetics and Genetic Diseases Diagnosis Center, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Ozlem Bozkurt (O)

Department of Medical Pathology, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Sibel Cetintas (S)

Department of Radiation Oncology, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Erdem Cubukcu (E)

Department of Medical Oncology, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Adem Deligonul (A)

Department of Medical Oncology, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Berkcan Dogan (B)

Department of Medical Genetics and Genetic Diseases Diagnosis Center, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.
Department of Translational Medicine, Bursa Uludag University Institute of Health Sciences, Bursa, Turkey.

Cemre Ornek Erguzeloglu (C)

Department of Translational Medicine, Bursa Uludag University Institute of Health Sciences, Bursa, Turkey.

Turkkan Evrensel (T)

Department of Translational Medicine, Bursa Uludag University Institute of Health Sciences, Bursa, Turkey.
Department of Medical Oncology, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Sehsuvar Gokgoz (S)

Department of General Surgery, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Kazim Senol (K)

Department of General Surgery, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Sahsine Tolunay (S)

Department of Medical Pathology, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Esra Akyurek (E)

Department of Medical Genetics, Erciyes University Faculty of Medicine, Kayseri, Turkey.

Neslihan Basgoz (N)

Department of Medical Genetics, Erciyes University Faculty of Medicine, Kayseri, Turkey.

Nuriye Gökçe (N)

Department of Medical Genetics, Erciyes University Faculty of Medicine, Kayseri, Turkey.

Bilge Dundar (B)

Department of Medical Genetics, Erciyes University Faculty of Medicine, Kayseri, Turkey.
Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, United States of America.

Figen Ozturk (F)

Department of Pathology, Erciyes University Faculty of Medicine, Kayseri, Turkey.

Duygu Taskin (D)

Department of Medical Genetics, Erciyes University Faculty of Medicine, Kayseri, Turkey.

Mercan Demirtas (M)

Mikrogen Genetic Diagnosis Laboratory, Ankara, Turkey.

Murat Cag (M)

Department of Vascular Surgery and Transplantation, Strasbourg University Nouvel Hospital, Strasbourg, France.

Omer Diker (O)

Department of Medical Oncology, Near East University Faculty of Medicine, Nicosia, Cyprus.

Polat Olgun (P)

Department of Medical Oncology, Near East University Faculty of Medicine, Nicosia, Cyprus.

Sevcan Tug Bozdogan (S)

Cukurova University AGENTEM (Adana Genetic Diseases Diagnosis and Treatment Center), Adana, Turkey.
Department of Medical Genetics, Cukurova University Faculty of Medicine, Adana, Turkey.

Munis Dundar (M)

Department of Medical Genetics, Erciyes University Faculty of Medicine, Kayseri, Turkey.

Atil Bisgin (A)

Cukurova University AGENTEM (Adana Genetic Diseases Diagnosis and Treatment Center), Adana, Turkey.
Department of Medical Genetics, Cukurova University Faculty of Medicine, Adana, Turkey.

Sehime Gulsun Temel (SG)

Department of Medical Genetics and Genetic Diseases Diagnosis Center, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.
Department of Translational Medicine, Bursa Uludag University Institute of Health Sciences, Bursa, Turkey.

Classifications MeSH