Modeling the biomechanics of laser corneal refractive surgery.


Journal

Journal of the mechanical behavior of biomedical materials
ISSN: 1878-0180
Titre abrégé: J Mech Behav Biomed Mater
Pays: Netherlands
ID NLM: 101322406

Informations de publication

Date de publication:
09 2023
Historique:
received: 24 01 2023
revised: 27 03 2023
accepted: 26 06 2023
medline: 8 8 2023
pubmed: 8 7 2023
entrez: 7 7 2023
Statut: ppublish

Résumé

We present a finite element model of the human cornea used to simulate corneal refractive surgery according to the three most diffused laser procedures, i. e., photo-refractive keratectomy (PRK), laser in-situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE). The geometry used for the model is patient-specific in terms of anterior and posterior surfaces of the cornea and intrastromal surfaces originated by the planned intervention. The customization of the solid model prior to finite element discretization avoids the struggling difficulties associated with the geometrical modification induced by cutting, incision and thinning. Important features of the model include the identification of the stress-free geometry and an adaptive compliant limbus to account for the surrounding tissues. By the way of simplification, we adopt a Hooke material model extended to the finite kinematics, and consider only the preoperative and short-term postoperative conditions, disregarding the remodeling and material evolution aspects typical of biological tissues. Albeit simple and incomplete, the approach demonstrates that the post-operative biomechanical state of the cornea, after the creation of a flap or the removal of a small lenticule, is strongly modified with respect to the preoperative state and characterized by displacement irregularities and stress localizations.

Identifiants

pubmed: 37418971
pii: S1751-6161(23)00351-X
doi: 10.1016/j.jmbbm.2023.105998
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

105998

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Andrea Montanino (A)

Department of Structures for Engineering and Architecture, University of Naples "Federico II", Via Toledo 402, Napoli, Italy. Electronic address: andrea.montanino@unina.it.

Sanne van Overbeeke (S)

Department of Mechanical Engineering, University of Technology Eindhoven, 5612 AZ Eindhoven, The Netherlands. Electronic address: s.v.overbeeke@student.tue.nl.

Anna Pandolfi (A)

Department of Civil and Environmental Engineering, Politecnico di Milano, 20133 Milano, Italy. Electronic address: anna.pandolfi@polimi.it.

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Classifications MeSH