Treatment of relapsing multiple sclerosis in Hungary - consensus recommendation from the Hungarian neuroimmunology society.


Journal

Orphanet journal of rare diseases
ISSN: 1750-1172
Titre abrégé: Orphanet J Rare Dis
Pays: England
ID NLM: 101266602

Informations de publication

Date de publication:
07 Jul 2023
Historique:
received: 04 04 2023
accepted: 18 06 2023
medline: 10 7 2023
pubmed: 8 7 2023
entrez: 7 7 2023
Statut: epublish

Résumé

Multiple sclerosis (MS) may impact quality of life, careers and family plans of the affected individuals. The current treatments with disease modifying therapies aim to prevent people with MS (pwMS) from disability accumulation and progression. Different countries have different reimbursement policies resulting in inequalities in patient care among geographical regions. Access to anti-CD20 therapies for relapsing MS is restricted in Hungary because therapy of individual cases only is reimbursed. In the light of the latest research and national guidelines, 17 Hungarian MS experts agreed on 8 recommendations regarding relapsing pwMS using the Delphi round method. Strong agreement (> 80%) was achieved in all except one recommendation after three rounds, which generated a fourth Delphi round. The experts agreed on treatment initiation, switch, follow-up and discontinuation, as well as on special issues such as pregnancy, lactation, elderly population, and vaccination. Well-defined national consensus protocols may facilitate dialogue between policymakers and healthcare professionals and thus contribute to better patient care in the long run.

Identifiants

pubmed: 37420270
doi: 10.1186/s13023-023-02789-0
pii: 10.1186/s13023-023-02789-0
pmc: PMC10329288
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

183

Informations de copyright

© 2023. The Author(s).

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Auteurs

Cecilia Rajda (C)

Department of Neurology, Albert Szent-Györgyi Health Centre, University of Szeged, Semmelweis u.6, Szeged, 6725, Hungary. rajda.cecilia@med.u-szeged.hu.

Csilla Rózsa (C)

Department of Neurology, Jahn Ferenc Teaching Hospital, Köves u. 1, Budapest, 1204, Hungary.

Andrea Mike (A)

Department of Neurology, Szent Borbála Hospital, Dózsa György u. 77, Tatabánya, 2800, Hungary.

Gábor Lovas (G)

Department of Neurology, Jahn Ferenc Teaching Hospital, Köves u. 1, Budapest, 1204, Hungary.

Zsolt Mezei (Z)

Department of Neurology, Faculty of Medicine, Semmelweis University, Balassa u. 6, Budapest, 1083, Hungary.

Gábor Jakab (G)

Department of Neurology, Uzsoki Hospital, Uzsoki u. 29-41, Budapest, 1145, Hungary.

Péter Ács (P)

Department of Neurology, Medical School, University of Pécs, Rét u. 2, Pécs, 7623, Hungary.

Gábor Rum (G)

Petz Aladár Department of Neurology, County Teaching Hospital, Vasvári Pál u. 2-4, Győr, 9024, Hungary.

Magdolna Simó (M)

Department of Neurology, Faculty of Medicine, Semmelweis University, Balassa u. 6, Budapest, 1083, Hungary.

Zita Jobbágy (Z)

Department of Neurology, Bács-Kiskun County Teaching Hospital, Kecskemét, Nyíri u. 38, Kecskemét, 6000, Hungary.

Zita Bíró (Z)

Department of Neurology, Flór Ferenc Hospital, Semmelweis tér 1, Kistarcsa, 2143, Hungary.

Anita Trauninger (A)

Department of Neurology, Medical School, University of Pécs, Rét u. 2, Pécs, 7623, Hungary.

Piroska Imre (P)

Department of Neurology, Csolnoky Ferenc Hospital, Kórház u. 1, Veszprém, 8200, Hungary.

Klotild Mátyás (K)

Department of Neurology, Markhot Ferenc Teaching Hospital, Knézich K. u. 1, Eger, 3300, Hungary.

István Deme (I)

Department of Neurology, Kaposi Mór Teaching Hospital, Tallián Gyula u 20-32, Kaposvár, 7400, Hungary.

Zsolt Illés (Z)

Department of Neurology, Odense University Hospital, Institute of Clinical Research, University of Southern Denmark, Winslows vej 4, Odense, 5000, Denmark.

Tunde Csepany (T)

Department of Neurology, Faculty of Medicine, University of Debrecen, Móricz Zs. Krt. 22, Debrecen, 4032, Hungary.

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Classifications MeSH