Risk Factors for Ischemic Stroke After Acute Coronary Syndrome.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
18 07 2023
Historique:
medline: 19 7 2023
pubmed: 8 7 2023
entrez: 8 7 2023
Statut: ppublish

Résumé

Background Stroke incidence is elevated after acute coronary syndromes (ACS). The aim of this study was to characterize risk factors related to ischemic stroke (IS) after ACS. Methods and Results We conducted a retrospective registry study based on the data of 8049 consecutive patients treated for ACS between 2007 and 2018 in Tays Heart Hospital with a follow-up until December 31, 2020. Potential risk factors were identified by in-depth review of written hospital records and causes-of-death registry data maintained by Statistics Finland. The association between individual risk factors, early-onset IS (0-30 days after ACS, n=82), and late-onset IS (31 days to 14 years after ACS, n=419) were analyzed using logistic regression and subdistribution hazard analysis. In multivariable analysis, the most substantial risk factors for early- and late-onset IS were previous stroke, atrial fibrillation or flutter, and heart failure status depicted by the Killip classification. Left ventricular ejection fraction and coronary artery disease severity were significant risk factors for early-onset IS; age and peripheral artery disease were significant risk factors for late-onset IS. The risk of early-onset IS with ≥6 CHA

Identifiants

pubmed: 37421266
doi: 10.1161/JAHA.122.028787
pmc: PMC10382101
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e028787

Commentaires et corrections

Type : ErratumIn

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Auteurs

Matilda Hurskainen (M)

Faculty of Medicine and Health Technology Tampere University Tampere Finland.

Juho Tynkkynen (J)

Department of Radiology Tampere University Hospital Tampere Finland.
Centre of Vascular Surgery and Interventional Radiology Tampere University Hospital Tampere Finland.

Markku Eskola (M)

Faculty of Medicine and Health Technology Tampere University Tampere Finland.
Tays Heart Hospital Tampere University Hospital Tampere Finland.

Terho Lehtimäki (T)

Faculty of Medicine and Health Technology Tampere University Tampere Finland.
Department of Clinical Chemistry Fimlab Laboratories Tampere Finland.
Finnish Cardiovascular Research Center Tampere Tampere Finland.

Jussi Hernesniemi (J)

Faculty of Medicine and Health Technology Tampere University Tampere Finland.
Tays Heart Hospital Tampere University Hospital Tampere Finland.
Finnish Cardiovascular Research Center Tampere Tampere Finland.

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Classifications MeSH