Complete Blood Count Markers and C-Reactive Protein as Predictors of Testicular Viability in the Event of Testicular Torsion in Adults.


Journal

Urologia internationalis
ISSN: 1423-0399
Titre abrégé: Urol Int
Pays: Switzerland
ID NLM: 0417373

Informations de publication

Date de publication:
2023
Historique:
received: 06 02 2023
accepted: 15 05 2023
medline: 12 9 2023
pubmed: 10 7 2023
entrez: 9 7 2023
Statut: ppublish

Résumé

The association between blood markers and testicular viability after testicular torsion (TT) is not well known. We evaluated the role of complete blood count markers and C-reactive protein (CRP) in predicting testicular viability after TT. Fifty men, ≥18 years of age, operated for TT between the years 2015-2020 were enrolled. Blood markers including neutrophil-, lymphocyte-, and platelet count, and CRP were obtained. Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) were calculated. The study outcome was testicular salvage. Median age was 23 years (interquartile range [IQR]: 21, 31). Median duration of torsion was 10 h (IQR: 6, 42). Sonographic texture of the testis was homogenous in 27 (56%) patients and heterogenous in 21 (44%). During scrotal exploration, 36 patients (72%) underwent orchiopexy and 14 (28%) underwent orchiectomy. Patients who underwent orchiopexy were younger (22 years vs. 31 years, p = 0.009), had a shorter duration of torsion (median 8 h vs. 48 h, p < 0.001), and a homogenous texture on scrotal ultrasound (76.5 vs. 7.1%, p < 0.001). Median NLR, PLR, and CRP were higher among patients who underwent orchiectomy; however, these differences did not reach statistical significance. Patients with heterogenous echotexture were significantly more likely to undergo orchiectomy (odds ratio = 42, 95% confidence interval: 7, 831, adjusted p value = 0.009). We found no association between blood-based biomarkers and testicular viability after TT; however, testicular echotexture significantly predicted outcome.

Identifiants

pubmed: 37423214
pii: 000531145
doi: 10.1159/000531145
pmc: PMC10614481
doi:

Substances chimiques

C-Reactive Protein 9007-41-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

801-806

Informations de copyright

© 2023 The Author(s). Published by S. Karger AG, Basel.

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Auteurs

Eyal Barkai (E)

Department of Urology, Tel-Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel.
Department of Urology, Samson Assuta Ashdod University Hospital, Ashdod, Israel.
Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Snir Dekalo (S)

Department of Urology, Tel-Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel.

Ofer Yossepowitch (O)

Department of Urology, Tel-Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel.

Jacob Ben-Chaim (J)

Sackler School of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel.
Department of Pediatric Urology, Dana-Dwek Children's Hospital, Tel-Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel.

Yuval Bar-Yosef (Y)

Sackler School of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel.
Department of Pediatric Urology, Dana-Dwek Children's Hospital, Tel-Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel.

Avi Beri (A)

Department of Urology, Tel-Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel.

Roy Mano (R)

Department of Urology, Tel-Aviv Sourasky Medical Center, Tel Aviv-Yafo, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel Aviv-Yafo, Israel.

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Classifications MeSH