Cushing's Disease Associated With Partially Empty Sella Turcica Syndrome: A Case Report.
cushing’s disease
empty sella trucica syndrome
mri negative cushing disease
pituitary nodule
weight loss
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
accepted:
08
06
2023
medline:
10
7
2023
pubmed:
10
7
2023
entrez:
10
7
2023
Statut:
epublish
Résumé
The association between empty sella turcica (EST) syndrome and Cushing's disease has been rarely reported. It is plausible to hypothesize that EST syndrome in association with Cushing's disease can be attributed to intracranial hypertension. In this case report, we present a 47-year-old male patient who presented with weight loss, fatigue, easy bruising, acanthosis nigricans, and skin creases hyperpigmentation. Investigations revealed hypokalemia and confirmed the diagnosis of Cushing's disease. Magnetic resonance imaging (MRI) brain showed a partial EST syndrome and a new pituitary nodule as compared with previous brain imaging. Transsphenoidal surgery was pursued and was complicated by cerebrospinal fluid leakage. This case reflects the rare association of EST syndrome and Cushing's disease, suggesting the increased risk of postoperative complications in this setting and the diagnostic challenge that EST syndrome imposes. We review the literature for a possible mechanism of this association.
Identifiants
pubmed: 37425515
doi: 10.7759/cureus.40115
pmc: PMC10329283
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e40115Informations de copyright
Copyright © 2023, Habib et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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