History of tuberculosis disease is associated with genetic regulatory variation in Peruvians.

dendritic cells expression quantitative trait loci macrophages tuberculosis

Journal

medRxiv : the preprint server for health sciences
Titre abrégé: medRxiv
Pays: United States
ID NLM: 101767986

Informations de publication

Date de publication:
27 Jun 2023
Historique:
pubmed: 10 7 2023
medline: 10 7 2023
entrez: 10 7 2023
Statut: epublish

Résumé

A quarter of humanity is estimated to be latently infected with

Identifiants

DOI: 10.1101/2023.06.20.23291558 PMID: 37425785 PMC: PMC10327177
pubmed: 37425785
doi: 10.1101/2023.06.20.23291558
pmc: PMC10327177
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI049313
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI175614
Pays : United States
Organisme : NHGRI NIH HHS
ID : T32 HG002295
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI111224
Pays : United States

Auteurs

Sara Suliman (S)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Zuckerberg San Francisco General Hospital, Division of Experimental Medicine, University of California San Francisco, San Francisco, CA, USA.
Gladstone-UCSF Institute of Genomic Immunology, University of California San Francisco, San Francisco, CA, USA.
Chan Zuckerberg Initiative Biohub, San Francisco, CA, USA.

Victor E Nieto-Caballero (VE)

Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Undergraduate Program in Genomic Sciences, Center for Genomic Sciences, Universidad Nacional Autónoma de México (UNAM), Morelos 62210, Mexico.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Samira Asgari (S)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Kattya Lopez (K)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Socios En Salud Sucursal Peru, Lima, Peru.

Sarah K Iwany (SK)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Yang Luo (Y)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

Aparna Nathan (A)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Daniela Fernandez-Salinas (D)

Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Marcos Chiñas (M)

Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Chuan-Chin Huang (CC)

Department of Global Health and Social Medicine, and Division of Global Health Equity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Zibiao Zhang (Z)

Department of Global Health and Social Medicine, and Division of Global Health Equity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Segundo R León (SR)

Socios En Salud Sucursal Peru, Lima, Peru.
Medical Technology School and Global Health Research Institute, San Juan Bautista Private University, Lima, Perú.

Roger I Calderon (RI)

Socios En Salud Sucursal Peru, Lima, Peru.

Leonid Lecca (L)

Socios En Salud Sucursal Peru, Lima, Peru.

Megan Murray (M)

Department of Global Health and Social Medicine, and Division of Global Health Equity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Ildiko Van Rhijn (I)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

Soumya Raychaudhuri (S)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

D Branch Moody (DB)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Maria Gutierrez-Arcelus (M)

Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Classifications MeSH