Permafrost Immunity.

Cellular immunity Climate change Cytokine Storm Exhausted T cells Global warming Humoral immunity Immune allostasis Oral health Permafrost Virus-Induced Autoimmunity

Journal

Bioinformation
ISSN: 0973-2063
Titre abrégé: Bioinformation
Pays: Singapore
ID NLM: 101258255

Informations de publication

Date de publication:
2022
Historique:
received: 05 09 2022
revised: 30 09 2022
accepted: 30 09 2022
medline: 10 7 2023
pubmed: 10 7 2023
entrez: 10 7 2023
Statut: epublish

Résumé

Thawing permafrost is a serious and worrisome threat to the environment, because it releases trapped heavy metals and greenhouse gasses. Thawing permafrost is also a health threat because, in addition to releasing these noxious gasses, thawing permafrost may free novel and undiscovered antibiotic-resistant bacteria, viruses, fungi and parasites among a plethora of dormant pathogens. Our immune system is ill-prepared to counter these challenges, and will require significant adaptation, or allostasis, which can be subsumed under the generic term of permafrost immunity. Since most of the most gravely threatening pathogens released by thawing permafrost are likely to penetrate the organism through the oral cavity, permafrost immunity may first be identified in the oral mucosa.

Identifiants

pubmed: 37426494
doi: 10.6026/97320630018734
pii: 97320630018734
pmc: PMC10326340
doi:

Types de publication

Editorial

Langues

eng

Pagination

734-738

Informations de copyright

© 2022 Biomedical Informatics.

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Auteurs

Francesco Chiappelli (F)

Dental Group of Sherman Oaks, CA 91403 (www.oliviacajulisdds.com).

Jaden Penhaskashi (J)

West Valley Dental Implant Center, Encino, CA 91316 (minimallyinvasiveperio.com).

Classifications MeSH