Complementary charge-driven encapsulation of functional protein by engineered protein cages


Journal

Journal of materials chemistry. B
ISSN: 2050-7518
Titre abrégé: J Mater Chem B
Pays: England
ID NLM: 101598493

Informations de publication

Date de publication:
19 Jul 2023
Historique:
medline: 10 7 2023
pubmed: 10 7 2023
entrez: 10 7 2023
Statut: epublish

Résumé

Charge-driven inclusion complex formation in live cells was examined using a degradation-prone fluorescent protein and a series of protein cages. The results show that sufficiently strong host-guest ionic interaction and an intact shell-like structure are crucial for the protective guest encapsulation.

Identifiants

pubmed: 37427706
doi: 10.1039/d3tb00754e
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6540-6546

Auteurs

Daniel Zakaszewski (D)

Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Gronostajowa 7A, 30387 Krakow, Poland. yusuke.azuma@uj.edu.pl.
Doctoral School of Exact and Natural Sciences, Jagiellonian University, Prof. S. Łojasiewicza 11, 30348 Krakow, Poland.

Lukasz Koziej (L)

Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Gronostajowa 7A, 30387 Krakow, Poland. yusuke.azuma@uj.edu.pl.

Jędrzej Pankowski (J)

Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Gronostajowa 7A, 30387 Krakow, Poland. yusuke.azuma@uj.edu.pl.
Faculty of Biochemistry, Biophysics, sand Biotechnology, Jagiellonian University, Gronostajowa 7, 30387 Krakow, Poland.

V Vishal Malolan (VV)

Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Gronostajowa 7A, 30387 Krakow, Poland. yusuke.azuma@uj.edu.pl.
Doctoral School of Exact and Natural Sciences, Jagiellonian University, Prof. S. Łojasiewicza 11, 30348 Krakow, Poland.

Nina Gämperli (N)

Laboratory of Organic Chemistry, ETH Zurich, 8093 Zurich, Switzerland.

Jonathan G Heddle (JG)

Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Gronostajowa 7A, 30387 Krakow, Poland. yusuke.azuma@uj.edu.pl.

Donald Hilvert (D)

Laboratory of Organic Chemistry, ETH Zurich, 8093 Zurich, Switzerland.

Yusuke Azuma (Y)

Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Gronostajowa 7A, 30387 Krakow, Poland. yusuke.azuma@uj.edu.pl.
Laboratory of Organic Chemistry, ETH Zurich, 8093 Zurich, Switzerland.

Classifications MeSH