Topical Tranexamic Acid in Primary Breast Augmentation Surgery: Short- and Long-term Outcomes.


Journal

Aesthetic surgery journal
ISSN: 1527-330X
Titre abrégé: Aesthet Surg J
Pays: England
ID NLM: 9707469

Informations de publication

Date de publication:
10 Jul 2023
Historique:
received: 08 06 2023
revised: 03 07 2023
accepted: 03 07 2023
medline: 10 7 2023
pubmed: 10 7 2023
entrez: 10 7 2023
Statut: aheadofprint

Résumé

Breast augmentation mammoplasty (BAM) remains to be the most popular cosmetic procedure done worldwide. Bleeding in this procedure increases the chance of capsular contracture. Tranexamic acid (TXA), an anti-fibrinolytic, has been widely used by other surgical specialties to reduce bleeding. We aimed to evaluate the use of TXA in BAM surgery. This is a single-surgeon case series of all patients who underwent primary BAM from March 2017 to March 2018 and received topical TXA spray to the implant pocket prior to implant insertion. Early postoperative complications and long-term outcomes, such as capsular contracture and revision surgery, were recorded and described. Two hundred and eighty-eight patients were included in the study with an overall complication rate of 2.8% over 5 years. No patients had postoperative bleeding or hematoma formation. One patient had a seroma, managed with ultrasound drainage. Complications requiring re-operation included rippling (3, 1.0%), pocket revision (2, 0.7%), capsule contracture (1, 0.3%) and rupture (1, 0.3%). This study highlights the safety and potential benefits of the use of topical TXA in breast augmentation, with low bleeding and capsular contracture rates.

Sections du résumé

BACKGROUND BACKGROUND
Breast augmentation mammoplasty (BAM) remains to be the most popular cosmetic procedure done worldwide. Bleeding in this procedure increases the chance of capsular contracture. Tranexamic acid (TXA), an anti-fibrinolytic, has been widely used by other surgical specialties to reduce bleeding.
OBJECTIVES OBJECTIVE
We aimed to evaluate the use of TXA in BAM surgery.
METHODS METHODS
This is a single-surgeon case series of all patients who underwent primary BAM from March 2017 to March 2018 and received topical TXA spray to the implant pocket prior to implant insertion. Early postoperative complications and long-term outcomes, such as capsular contracture and revision surgery, were recorded and described.
RESULTS RESULTS
Two hundred and eighty-eight patients were included in the study with an overall complication rate of 2.8% over 5 years. No patients had postoperative bleeding or hematoma formation. One patient had a seroma, managed with ultrasound drainage. Complications requiring re-operation included rippling (3, 1.0%), pocket revision (2, 0.7%), capsule contracture (1, 0.3%) and rupture (1, 0.3%).
CONCLUSIONS CONCLUSIONS
This study highlights the safety and potential benefits of the use of topical TXA in breast augmentation, with low bleeding and capsular contracture rates.

Identifiants

pubmed: 37427875
pii: 7222144
doi: 10.1093/asj/sjad219
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentIn

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of The Aesthetic Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Auteurs

Sarah Lonie (S)

Department of Plastic Surgery, East Sydney Private Hospital, Sydney, Australia.

Gerald Marion Abesamis (GM)

Division of Burns and Division of Plastic Surgery, Department of Surgery, University of the Philippines - Philippine General Hospital, Manila, Philippines.

Jenaleen Law (J)

Department of Plastic and Reconstructive Surgery, Macquarie University, Sydney, Australia.

Mohammad Hassan Mohaghegh (MH)

Department of Plastic and Reconstructive Surgery, Macquarie University, Sydney, Australia.

Karen Vickery (K)

Department of Plastic and Reconstructive Surgery, Macquarie University, Sydney, Australia.

Anand Deva (A)

Department of Plastic and Reconstructive Surgery, Macquarie University, Sydney, Australia Aesthetic Surgery Journal.

Kourosh Tavakoli (K)

Department of Plastic Surgery, East Sydney Private Hospital, Sydney, Australia.

Classifications MeSH