Neural patterns of conscious visual awareness in the Riddoch syndrome.
Awareness
Blindsight
Consciousness
MT +
Neural patterns
Statokinetic dissociation
V5
Visual motion
Journal
Journal of neurology
ISSN: 1432-1459
Titre abrégé: J Neurol
Pays: Germany
ID NLM: 0423161
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
12
06
2023
accepted:
30
06
2023
revised:
30
06
2023
medline:
23
10
2023
pubmed:
11
7
2023
entrez:
10
7
2023
Statut:
ppublish
Résumé
The Riddoch syndrome is one in which patients blinded by lesions to their primary visual cortex can consciously perceive visual motion in their blind field, an ability that correlates with activity in motion area V5. Our assessment of the characteristics of this syndrome in patient ST, using multimodal MRI, showed that: 1. ST's V5 is intact, receives direct subcortical input, and decodable neural patterns emerge in it only during the conscious perception of visual motion; 2. moving stimuli activate medial visual areas but, unless associated with decodable V5 activity, they remain unperceived; 3. ST's high confidence ratings when discriminating motion at chance levels, is associated with inferior frontal gyrus activity. Finally, we report that ST's Riddoch Syndrome results in hallucinatory motion with hippocampal activity as a correlate. Our results shed new light on perceptual experiences associated with this syndrome and on the neural determinants of conscious visual experience.
Identifiants
pubmed: 37429978
doi: 10.1007/s00415-023-11861-5
pii: 10.1007/s00415-023-11861-5
pmc: PMC10576735
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5360-5371Subventions
Organisme : Leverhulme Trust
ID : RPG-2020-022
Informations de copyright
© 2023. The Author(s).
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