Decoding Hypercalcemia and Renal Stones in a Young Adult: Could it be Dent's Disease?

Dent’s disease chronic kidney disease nephrolithiasis

Journal

Clinical medicine insights. Case reports
ISSN: 1179-5476
Titre abrégé: Clin Med Insights Case Rep
Pays: United States
ID NLM: 101531893

Informations de publication

Date de publication:
2023
Historique:
received: 12 03 2023
accepted: 31 05 2023
medline: 12 7 2023
pubmed: 12 7 2023
entrez: 12 7 2023
Statut: epublish

Résumé

Dent's disease is a rare genetic kidney disorder characterized by proximal tubular dysfunction, nephrocalcinosis, recurrent nephrolithiasis, and chronic kidney disease. Hypercalcemia is a rare finding in this disease. In this report, we present a case of possible Dent's disease in a young adult male with hypercalcemia and chronic kidney disease. The diagnosis was evoked based on the presence of low-molecular-weight proteinuria, kidney stones, and renal failure. This case underscores the significance of considering Dent's disease as a potential diagnosis, even in patients with chronic renal disease who exhibit hypercalcemia. It also emphasizes the importance of regular monitoring and management of patients with this condition to prevent further complications.

Identifiants

pubmed: 37435354
doi: 10.1177/11795476231182591
pii: 10.1177_11795476231182591
pmc: PMC10331178
doi:

Types de publication

Case Reports

Langues

eng

Pagination

11795476231182591

Informations de copyright

© The Author(s) 2023.

Déclaration de conflit d'intérêts

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Références

Kidney Int. 2000 Jan;57(1):240-9
pubmed: 10620205
Curr Pediatr Rev. 2014;10(2):95-100
pubmed: 25088262
Nephrol Dial Transplant. 2012 Dec;27(12):4273-87
pubmed: 23235953
Prim Care. 2008 Jun;35(2):369-91, vii
pubmed: 18486720
Hum Mol Genet. 1999 Feb;8(2):247-57
pubmed: 9931332
Indian Pediatr. 2020 May 15;57(5):415-419
pubmed: 32221050
Nephron Physiol. 2009;112(2):p27-36
pubmed: 19390221
Kidney Int. 2000 Mar;57(3):787-93
pubmed: 10720930
Intractable Rare Dis Res. 2017 Feb;6(1):41-45
pubmed: 28357180
Annu Rev Physiol. 2005;67:779-807
pubmed: 15709978
Arch Dis Child. 1964 Jun;39:240-9
pubmed: 14169453
QJM. 1994 Aug;87(8):473-93
pubmed: 7922301
Kidney Int. 2008 Jun;73(11):1320-3
pubmed: 18235437
Orphanet J Rare Dis. 2010 Oct 14;5:28
pubmed: 20946626
QJM. 1998 Jan;91(1):5-12
pubmed: 9519207

Auteurs

Meriam Hajji (M)

Department of Medecine A, Charles Nicolle Hospital, Tunis, Tunisia.
Laboratory of Kidney Pathology LR00SP01, Charles Nicolle Hospital, Tunis, Tunisia.
Faculty of Medicine de Tunis Université Tunis El Manar, Tunis, Tunisia.

Hayet Kaaroud (H)

Department of Medecine A, Charles Nicolle Hospital, Tunis, Tunisia.
Laboratory of Kidney Pathology LR00SP01, Charles Nicolle Hospital, Tunis, Tunisia.
Faculty of Medicine de Tunis Université Tunis El Manar, Tunis, Tunisia.

Fethi Ben Hamida (F)

Laboratory of Kidney Pathology LR00SP01, Charles Nicolle Hospital, Tunis, Tunisia.

Ezzeddine Abderrahim (E)

Department of Medecine A, Charles Nicolle Hospital, Tunis, Tunisia.
Faculty of Medicine de Tunis Université Tunis El Manar, Tunis, Tunisia.

Classifications MeSH