Metabolomics Analysis Reveals the Potential Relationship Between Sow Colostrum and Neonatal Serum Metabolites in Different Pig Breeds.
breeds
colostrum
metabolome
mother-offspring integration
neonatal piglets
Journal
Molecular nutrition & food research
ISSN: 1613-4133
Titre abrégé: Mol Nutr Food Res
Pays: Germany
ID NLM: 101231818
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
revised:
18
04
2023
received:
07
10
2022
medline:
17
8
2023
pubmed:
12
7
2023
entrez:
12
7
2023
Statut:
ppublish
Résumé
Colostrum composition is an important indicator of newborn piglet survival and growth. However, limited information is available on the association between colostrum metabolites in sows and serum metabolites in neonates. Therefore, the present study aims to determine the metabolites in the colostrum of sows, in the serum of their offspring piglets, and mother-offspring metabolite correlations in different pig breeds. Colostrum and serum samples are collected from 30 sows and their piglets from three pig breeds (Taoyuan black, TB; Xiangcun black, XB; and Duroc) to analyze the targeted metabolomics. This study identifies 191 metabolites in the colostrum of sows, including fatty acids, amino acids, bile acids, carnitines, carbohydrates, and organic acids, and the concentrations of these metabolites are highest in the TB pigs. Metabolite profiles in sow colostrum and piglet serum differ among Duroc, TB, and XB pigs, and the matching metabolites are mainly enriched in the digestive system and transportation pathways. Furthermore, identification of the associations between metabolites in the colostrum of sows and their neonate sera suggests that metabolite compounds from colostrum are transported to suckling piglets. The present study findings deepen the understanding of the composition of sow colostrum metabolites and the transportation of metabolites from sow colostrum to piglets. The findings also provide insight regarding the development of dietary formulas that resemble the sow colostrum for newborn animals to maintain health and improve the early growth of offspring.
Identifiants
pubmed: 37436085
doi: 10.1002/mnfr.202200677
doi:
Substances chimiques
Fatty Acids
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2200677Informations de copyright
© 2023 Wiley-VCH GmbH.
Références
M. Walls Castellanos, E. C. Claud, Trends Mol. Med. 2021, 27, 1175.
K. Blanchette, Bioethics 2021, 35, 207.
R. Nardone, C. Florea, Y. Höller, F. Brigo, V. Versace, P. Lochner, S. Golaszewski, E. Trinka, Zoology 2017, 123, 101.
M. A. K. Azad, P. Huang, G. Liu, W. Ren, T. Teklebrh, W. Yan, X. Zhou, Y. Yin, Amino Acids 2018, 50, 3.
V. Demecková, D. Kelly, A. G. P. Coutts, P. H. Brooks, A. Campbell, Int. J. Food. Microbiol. 2002, 79, 85.
L. J. Pedersen, P. Berg, G. Jørgensen, I. L. Andersen, J. Anim. Sci. 2011, 89, 1207.
P. Juthamanee, P. Tummaruk, Livest. Sci. 2021, 251, 104630.
O. Ballard, A. L. Morrow, Pediatr. Clin. North. Am. 2013, 60, 49.
R. Inoue, T. Tsukahara, Anim. Sci. J. 2021, 92, e13618.
H. Quesnel, C. Farmer, N. Devillers, Livest. Sci. 2012, 146, 105.
N. Martínez-Boixaderas, L. Garza-Moreno, M. Sibila, J. Segalés, Porc. Health Manag. 2022, 8, 11.
C. Ren, J. Jin, X. Wang, Y. Zhang, Q. Jin, Int. Dairy J. 2022, 126, 105250.
G. Picone, M. Zappaterra, D. Luise, A. Trimigno, F. Capozzi, V. Motta, R. Davoli, L. Nanni Costa, P. Bosi, P. Trevisi, J. Anim. Sci. Biotechnol. 2018, 9, 23.
Q. Chen, W. Zhang, J. Cai, Y. Ni, L. Xiao, J. Zhang, Gene 2022, 808, 145978.
Y. Liu, X. Yang, X. Jing, X. He, L. Wang, Y. Liu, D. Liu, Int. J. Mol. Sci. 2018, 19, 21.
Y. Hao, J. Wang, D. Teng, X. Wang, R. Y. Mao, Y. Na, X. Ma, Biochem. Cell. Biol. 2020, 99, 66.
S. Hosseinkhani, B. Arjmand, A. Dilmaghani-Marand, S. Mohammadi Fateh, H. Dehghanbanadaki, N. Najjar, S. Alavi-Moghadam, R. Ghodssi-Ghassemabadi, E. Nasli-Esfahani, F. Farzadfar, B. Larijani, F. Razi, Sci. Rep. 2022, 12, 8418.
G. J. Patti, O. Yanes, G. Siuzdak, Nat. Rev. Mol. Cell. Biol. 2013, 13, 263.
A. Socha-Banasiak, S. Pierzynowski, J. Woliński, D. Grujic, M. Boryczka, P. Grzesiak, P. Szczurek, E. Czkwianianc, B. Westrom, K. Goncharova, J. Biol. Regul. Homeost. Agents 2017, 31, 87.
D. Luise, V. Cardenia, M. Zappaterra, V. Motta, P. Bosi, M. T. Rodriguez-Estrada, P. Trevisi, J. Agric. Food. Chem. 2018, 66, 12911.
L. Amatucci, D. Luise, F. Correa, P. Bosi, P. Trevisi, Animals 2022, 12, 1230.
C. Tan, Z. Zhai, X. Ni, H. Wang, Y. Ji, T. Tang, W. Ren, H. Long, B. Deng, J. Deng, Y. Yin, Sci. Rep. 2018, 8, 10712.
L. V. Mennitti, J. L. Oliveira, C. A. Morais, D. Estadella, L. M. Oyama, C. M. Oller do Nascimento, L. P. Pisani, J. Nutr. Biochem. 2015, 26, 99.
M. Nepal, C. Ma, G. Xie, W. Jia, P. Fei, Aging 2018, 10, 1506.
B. Darcy-Vrillon, L. Posho, M. T. Morel, F. Bernard, F. Blachier, J. C. Meslin, P. H. Duée, Pediatr. Res. 1994, 36, 175.
W. Durante, Nutrients 2019, 11, 2092.
A. Slominski, M. A. Zmijewski, J. Pawelek, Pigment Cell Melanoma Res. 2012, 25, 14.
K. Fujii, H. Zhang, K. Usuda, G. Watanabe, K. Nagaoka, J. Cell. Physiol. 2015, 230, 2755.
H. Meng, N. R. Matthan, D. Wu, L. Li, J. Rodríguez-Morató, R. Cohen, J. M. Galluccio, G. G. Dolnikowski, A. H. Lichtenstein, Am. J. Clin. Nutr. 2019, 110, 305.
M. Beaumont, F. Blachier, in Amino Acids in Nutrition and Health: Amino Acids in Systems Function and Health (Ed.: G. Wu), Springer International Publishing, Cham 2020, p. 1.
Q. He, X. Kong, G. Wu, P. Ren, Y. Wu, Amino Acids 2008, 37, 199.
T. Ohkoda, K. Yoshida, D. Ijiri, A. Ohtsuka, Anim. Sci. J. 2021, 92, e13655.
C. Thomas, R. Tampé, Annu. Rev. Biochem. 2020, 89, 605.
C. Tóthová, R. Link, P. Kyzeková, O. Nagy, Sci. Rep. 2021, 11, 17539.
S. Wang, P. Wu, K. Wang, X. Ji, D. Chen, Y. Liu, J. Ding, X. Xu, G. Tang, Theriogenology 2022, 183, 10.
Y. Qi, X. Zhao, D. Huang, X. Pan, Y. Yang, H. Zhao, H. Hu, G. Cheng, J. Agric. Food. Chem. 2018, 66, 7200.
R. K. Buddington, P. T. Sangild, B. Hance, E. Y. Huang, D. D. Black, J. Anim. Sci. 2012, 90, 290.
R. Huang, Z. Li, X. Zhu, P. Yan, D. Song, H. Yin, P. Hu, R. Lin, S. Wu, T. Meng, J. Zhang, Z. Huang, J. Cell. Mol. Med. 2020, 24, 10803.
X. W. Zhao, Y. X. Qi, D. W. Huang, X. C. Pan, G. L. Cheng, H. L. Zhao, Y. X. Yang, J. Dairy Sci. 2018, 101, 7168.
X. Meng, H. Pang, F. Sun, X. Jin, B. Wang, K. Yao, L. Yao, L. Wang, Z. Hu, Anal. Chem. 2021, 93, 10075.
J. Chong, O. Soufan, C. Li, I. Caraus, S. Li, G. Bourque, D. S. Wishart, J. Xia, Nucleic Acids Res. 2018, 46, W486.