Photodynamic therapy in the coadjuvant treatment of Sporothrix schenckii complex.
low-level laser therapy
photobiomodulation
photodynamic therapy
sporotrichosis
zoonosis
Journal
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
ISSN: 1754-4505
Titre abrégé: Spec Care Dentist
Pays: United States
ID NLM: 8103755
Informations de publication
Date de publication:
12 Jul 2023
12 Jul 2023
Historique:
revised:
15
06
2023
received:
08
04
2023
accepted:
02
07
2023
medline:
12
7
2023
pubmed:
12
7
2023
entrez:
12
7
2023
Statut:
aheadofprint
Résumé
Sporotrichosis, a zoonosis caused by animal, mainly cat, scratches or bites, is caused by fungi belonging to the Sporothrix complex. Treatment usually consists in antifungal administration, although treatment failure and hepatotoxicity reports have been noted. Alternative sporotrichosis treatment methods, such as antimicrobial photodynamic therapy (aPDT), may, therefore, be indicated. In this context, this study followed a 56-year-old male renal transplanted patient displaying disseminated sporotrichosis, presenting erythematous skin lesions with ulcerated backgrounds and hardened consistency on the nose, oral and scalp. The lesions were present for about 2 months and the patient coexisted with cats. Intravenous amphotericin B administration was initiated, and immunosuppression was suspended. Seven aPDT sessions were also performed in 48 h intervals on the oral lesions, employing 0.01% methylene blue gel as the photosensitizing agent. After the 4th aPDT session, the patient was discharged, amphotericin B administration was suspended, and the treatment was continued with itraconazole, without immunosuppression. Red laser was applied to the oral lesions after the 7th aPDT session. Significant lesion improvement was observed after the final aPDT session and complete palate lesion repair was noted after two red laser sessions. These findings indicate that aPDT is a valuable strategy as an adjunct sporotrichosis treatment.
Types de publication
Case Reports
Langues
eng
Informations de copyright
© 2023 Special Care Dentistry Association and Wiley Periodicals LLC.
Références
Orofino-Costa R, Rodrigues AM, de Macedo PM, Bernardes-Engemann AR. Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics. An Bras Dermatol. 2017;92:606-620. doi:10.1590/abd1806-4841.2017279
Macêdo-Sales PA, Souto SRLS, Destefani CA, et al. Domestic feline contribution in the transmission of Sporothrix in Rio de Janeiro State, Brazil: a comparison between infected and non-infected populations. BMC Vet Res. 2018;14:19. doi:10.1186/s12917-018-1340-4
Freitas DFS, De Siqueira Hoagland B, Do Valle ACF, et al. Sporotrichosis in HIV-infected patients: report of 21 cases of endemic sporotrichosis in Rio de Janeiro. Brazil Med Mycol. 2012;50:170-178. doi:10.3109/13693786.2011.596288
Hernández-Castro R, Pinto-Almazán R, Arenas R, et al. Epidemiology of clinical sporotrichosis in the Americas in the last ten years. J Fungi (Basel). 2022;8:588. doi:10.3390/jof8060588
Chakrabarti A, Bonifaz A, Gutierrez-Galhardo MC, Mochizuki T, Li S. Global epidemiology of sporotrichosis. Med Mycol. 2014:3-14.
Aarestrup FM, Guerra RO, Vieira BJ, Cunha R. Oral manifestation of sporotrichosis in AIDS patients [Internet]. Oral Dis. 2001;7:134-136. www.munksgaard.dk
Fontes PC, Kitakawa D, Carvalho YR, Brandão AA, Cabral LA, Almeida JD. Sporotrichosis in an HIV-positive man with oral lesions: a case report. Acta Cytol. 2007;51:648-650. doi:10.1159/000325818
Mario DAN, Denardi LB, Pereira DIB, Santurio JM, Alves SH. In vitro photodynamic inactivation of Sporothrix schenckii complex species. Med Mycol. 2014;52:770-773. doi:10.1093/mmy/myu041
Gilaberte Y, Aspiroz C, Carmen Alejandre M, et al. Cutaneous sporotrichosis treated with photodynamic therapy: an in vitro and in vivo study. Photomed Laser Surg. 2014;32:54-57. doi:10.1089/pho.2013.3590
Gursoy H, Ozcakir-Tomruk C, Tanalp J, Yılmaz S. Photodynamic therapy in dentistry: a literature review. Clin Oral Investig. 2013;17:1113-1125.
Teixeira IS, Leal FS, Tateno RY, Palma LF, Campos L. Photobiomodulation therapy and antimicrobial photodynamic therapy for orofacial lesions in patients with COVID-19: a case series. Photodiagnosis Photodyn Ther. 2021;34:102281. doi:10.1016/j.pdpdt.2021.102281
Furtado GS, Paschoal MAB, Santos Grenho LdoC, Lago ADN. Does pre-irradiation time influence the efficacy of antimicrobial photodynamic therapy? Photodiagnosis Photodyn Ther. 2020;31:101884. doi:10.1016/j.pdpdt.2020.101884
Martínez-Herrera E, Arenas R, Hernández-Castro R, Frías-De-león MG, Rodríguez-Cerdeira C. Uncommon clinical presentations of sporotrichosis: a two-case report. Pathogens. 2021;10:1249. doi:10.3390/pathogens10101249
Abrahão AC, Agostini M, de Oliveira TR, et al. Oral manifestations of sporotrichosis: a neglected disease. J Clin Exp Dent. 2023;15:82-87. doi:10.4317/jced.59040
Berlingieri G, Alvares CMA, Serrano RV, Palma LF, Campos L. Phototherapies for COVID-19-associated opportunistic oral infections. Photodiagnosis Photodyn Ther. 2022;37:102678. doi:10.1016/j.pdpdt.2021.102678
Afrasiabi S, Pourhajibagher M, Chiniforush N, Bahador A. Propolis nanoparticle enhances the potency of antimicrobial photodynamic therapy against Streptococcus mutans in a synergistic manner. Sci Rep. 2020;10:15560. doi:10.1038/s41598-020-72119-y
Carmello JC, Alves F, Basso FG, et al. Treatment of oral candidiasis using Photodithazine®-mediated photodynamic therapy in vivo. PLoS One. 2016;11:e0156947. doi:10.1371/journal.pone.0156947
Alves F, Alonso GC, Carmello JC, Mima EGdeO, Bagnato VS, Pavarina AC. Antimicrobial photodynamic therapy mediated by Photodithazine® in the treatment of denture stomatitis: a case report. Photodiagnosis Photodyn Ther. 2018;21:168-171. doi:10.1016/j.pdpdt.2017.11.018
Janeth Rimachi Hidalgo K, Cabrini Carmello J, Carolina Jordão C, et al. Antimicrobial photodynamic therapy in combination with nystatin in the treatment of experimental oral candidiasis induced by candida albicans resistant to fluconazole. Pharmaceuticals. 2019;12:140. doi:10.3390/ph12030140
Du M, Xuan W, Zhen X, et al. Antimicrobial photodynamic therapy for oral Candida infection in adult AIDS patients: a pilot clinical trial. Photodiagnosis Photodyn Ther. 2021;34:102310. doi:10.1016/j.pdpdt.2021.102310
Santos DSdeA, Galvão GS, Ribas PF, Peres MPSdeM, Franco JB. Photodynamic therapy in the treatment of oral lesions caused by paracoccidiomycosis. Photodiagnosis Photodyn Ther. 2022;37:102648. doi:10.1016/j.pdpdt.2021.102648
Tiburcio MA, Rocha AR, Romano RA, et al. In vitro evaluation of the cis-[Ru(phen)2(pPDIp)]2+⁎⁎ complex for antimicrobial photodynamic therapy against Sporothrix brasiliensis and Candida albicans. J Photochem Photobiol B. 2022;229:112414. doi:10.1016/j.jphotobiol.2022.112414