Technical Comment on "Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling".

Bumetanide / pharmacology Furosemide Molecular Conformation

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
14 07 2023
Historique:
medline: 14 7 2023
pubmed: 12 7 2023
entrez: 12 7 2023
Statut: ppublish

Résumé

Flygaard, Habeck and Nissen question claims on bumetanide and furosemide binding to sodium-potassium-chloride cotransporter NKCC1.

Identifiants

DOI: 10.1126/sciadv.adh0821 PMID: 37436990 PMC: PMC10337923
pubmed: 37436990
doi: 10.1126/sciadv.adh0821
pmc: PMC10337923
doi:

Substances chimiques

Bumetanide 0Y2S3XUQ5H
Furosemide 7LXU5N7ZO5

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadh0821

Références

Sci Adv. 2022 Oct 28;8(43):eabq0952
pubmed: 36306358
Nature. 2019 Aug;572(7770):488-492
pubmed: 31367042
Neuropharmacology. 2018 Dec;143:186-204
pubmed: 30248303
Nat Commun. 2022 May 18;13(1):2747
pubmed: 35585053
EMBO J. 2021 Jul 15;40(14):e107294
pubmed: 34031912
EMBO J. 2022 Dec 1;41(23):e110169
pubmed: 36239040

Auteurs

Rasmus Kock Flygaard (RK)

Danish Research Institute of Translational Neuroscience (DANDRITE), Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
ORCID: 0000-0002-4918-6438

Michael Habeck (M)

Danish Research Institute of Translational Neuroscience (DANDRITE), Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
ORCID: 0000-0002-4586-0499

Poul Nissen (P)

Danish Research Institute of Translational Neuroscience (DANDRITE), Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
ORCID: 0000-0003-0948-6628

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Sulfones › Sulfonamides › Bumétanide › Technical Comment on "Inhibition mechanism of...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Sulfones › Sulfonamides › Sulfamides › Furosémide › Technical Comment on "Inhibition mechanism of...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Technical Comment on "Inhibition mechanism of...