Cancer before and after the start of hemodialysis and association with mortality - an Eastern-European multicenter study.
Cancer
East European multicenter study
end-stage kidney disease
hemodialysis patients
mortality
risk
Journal
Renal failure
ISSN: 1525-6049
Titre abrégé: Ren Fail
Pays: England
ID NLM: 8701128
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
medline:
14
7
2023
pubmed:
13
7
2023
entrez:
13
7
2023
Statut:
ppublish
Résumé
East-European data on cancer in patients undergoing hemodialysis (HD) are scarce. This study aimed to assess the pattern of cancer and related mortality in patients with end-stage kidney disease (ESKD) undergoing HD. Retrospectively analyzing data from 7 HD centers, this study examined 1377 incident HD patients divided into three groups: no-cancers (NoC), cancers that occurred prior to HD initiation (CPI) and de novo cancer developed after HD initiation (DNC). Mortality risk and survival trends within groups were analyzed using Cox regression and Kaplan-Meier methods. In the cohort, 89.46% of the patients had no cancer (NoC group), 3.63% had cancer before (CPI group), and 6.89% had cancer after HD initiation (DNC group). The mean time from HD initiation to DNC diagnosis was 1 [2.75] years. Older age was associated with a higher risk of developing DNC ( East-European ESKD patients undergoing HD have a high incidence of de novo cancers whose primary cancer sites are the digestive and urinary tracts. Almost half of the HD patients with CPI have hematologic and digestive tract cancers. Age and CTIN were associated with cancer risk. Cancer is an independent risk factor for all-cause mortality in patients undergoing hemodialysis (HD).
Identifiants
pubmed: 37439202
doi: 10.1080/0886022X.2023.2232046
pmc: PMC10348028
doi:
Types de publication
Multicenter Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2232046Références
Open Life Sci. 2023 Feb 17;18(1):20220553
pubmed: 36820211
Clin Kidney J. 2020 Dec 22;14(1):23-35
pubmed: 33570513
Kidney Int. 2019 Aug;96(2):287-290
pubmed: 31200943
J Am Soc Nephrol. 2009 Jun;20(6):1341-50
pubmed: 19406977
Am J Epidemiol. 2020 Sep 1;189(9):942-950
pubmed: 32219380
Nephrol Dial Transplant. 2015 Jun;30(6):1028-37
pubmed: 25637641
Biomed Res Int. 2014;2014:647541
pubmed: 24689048
Pathol Biol (Paris). 2011 Oct;59(5):286-91
pubmed: 19896305
BMC Cancer. 2016 Jul 16;16:488
pubmed: 27421889
Kidney Int. 2021 Jul;100(1):182-195
pubmed: 33359055
Nephrology (Carlton). 2019 Apr;24(4):380-386
pubmed: 30394626
Kidney Int. 2019 Sep;96(3):555-567
pubmed: 31445584
BMC Nephrol. 2019 Mar 28;20(1):107
pubmed: 30922296
J Cancer. 2017 Jan 1;8(1):9-18
pubmed: 28123593
Nephrology (Carlton). 2018 Dec;23(12):1125-1130
pubmed: 28633195
Korean J Intern Med. 2020 Sep;35(5):1210-1219
pubmed: 32066223
Oncotarget. 2017 May 23;8(39):66601-66619
pubmed: 29029541
Am J Kidney Dis. 2015 May;65(5):763-72
pubmed: 25662835
Am J Kidney Dis. 2022 Oct;80(4):449-461
pubmed: 35500725
J Clin Med. 2020 Oct 12;9(10):
pubmed: 33053860
Kidney Int Suppl (2011). 2017 Jul;7(1):1-59
pubmed: 30675420
Front Cell Dev Biol. 2022 May 18;10:868715
pubmed: 35663394
Nephrol Dial Transplant. 2018 Oct 1;33(suppl_3):iii35-iii40
pubmed: 30281126
J Korean Med Sci. 2009 Jan;24 Suppl:S95-S101
pubmed: 19194570
Sci Rep. 2021 Feb 16;11(1):3929
pubmed: 33594123
Am J Kidney Dis. 2014 Jan;63(1):23-30
pubmed: 23993153
Aging Dis. 2017 Oct 1;8(5):611-627
pubmed: 28966805
Int J Cancer. 2017 Mar 1;140(5):1091-1101
pubmed: 27870055
Lancet. 1986 May 31;1(8492):1271-2
pubmed: 2872410
J Nephrol. 2010 May-Jun;23(3):253-62
pubmed: 20349418
Am J Kidney Dis. 2020 Oct;76(4):558-566
pubmed: 32305205
N Engl J Med. 2000 Jun 8;342(23):1686-92
pubmed: 10841870
Med Ultrason. 2023 Feb 07;:
pubmed: 36780602
Kidney Int. 2003 Mar;63(3):793-808
pubmed: 12631061
Lancet. 1999 Jul 10;354(9173):93-9
pubmed: 10408483
PLoS One. 2015 Apr 13;10(4):e0122856
pubmed: 25874862
Diagnostics (Basel). 2021 Apr 15;11(4):
pubmed: 33921123
Nephrol Dial Transplant. 2009 Oct;24(10):3225-31
pubmed: 19589786
PLoS One. 2018 Nov 20;13(11):e0207756
pubmed: 30458033