Effect of acute heat exposure on the pressor response to a voluntary hypoxic apnea.
blood pressure
heat exposure
pressor response
Journal
Journal of applied physiology (Bethesda, Md. : 1985)
ISSN: 1522-1601
Titre abrégé: J Appl Physiol (1985)
Pays: United States
ID NLM: 8502536
Informations de publication
Date de publication:
01 09 2023
01 09 2023
Historique:
pmc-release:
01
09
2024
medline:
14
8
2023
pubmed:
13
7
2023
entrez:
13
7
2023
Statut:
ppublish
Résumé
The pressor response induced by a voluntary hypoxic apnea is mediated largely by increased sympathetic outflow. The neural control of blood pressure is altered in recovery from acute heat exposure, but its effect on the pressor response to a voluntary hypoxic apnea has never been explored. Therefore, we tested the hypothesis that prior heat exposure would attenuate the pressor response induced by a voluntary hypoxic apnea. Eleven healthy adults (five women) were exposed to whole body passive heating (water-perfused suit) sufficient to increase body core temperature by 1.2°C. Voluntary hypoxic apneas were performed at baseline and in recovery when body core temperature returned to ≤ 0.3°C of baseline. Participants breathed gas mixtures of varying [Formula: see text] (21%, 16%, and 12%; randomized) for 1 min followed by a 15-s end-expiratory apnea. The change in arterial oxygen saturation during each apnea did not differ from baseline to recovery (
Identifiants
pubmed: 37439242
doi: 10.1152/japplphysiol.00245.2023
pmc: PMC10538993
doi:
Banques de données
figshare
['10.6084/m9.figshare.23654403']
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
542-548Subventions
Organisme : NIA NIH HHS
ID : R01 AG059314
Pays : United States
Organisme : NIA NIH HHS
ID : T32 AG020494
Pays : United States
Références
N Engl J Med. 2019 Apr 11;380(15):1442-1449
pubmed: 30970189
Compr Physiol. 2015 Jan;5(1):17-43
pubmed: 25589263
Am J Physiol Heart Circ Physiol. 2004 Nov;287(5):H2054-60
pubmed: 15242836
J Physiol. 2022 Aug;600(15):3603-3624
pubmed: 35731687
Chest. 2007 May;131(5):1406-13
pubmed: 17494791
Exp Physiol. 2020 Feb;105(2):302-311
pubmed: 31707732
Curr Hypertens Rep. 1999 Jun;1(3):268-73
pubmed: 10981077
Compr Physiol. 2015 Apr;5(2):561-77
pubmed: 25880505
Exp Physiol. 2015 Sep;100(9):1018-29
pubmed: 26132990
Curr Cardiol Rep. 2020 Jan 18;22(2):6
pubmed: 31955254
Auton Neurosci. 2016 Jan;194:38-45
pubmed: 26774324
Chest. 1990 Jan;97(1):33-8
pubmed: 2403899
J Clin Sleep Med. 2019 Feb 04;15(2):335-343
pubmed: 30736887
J Appl Physiol (1985). 2022 Dec 1;133(6):1394-1406
pubmed: 36302157
Physiol Rep. 2015 Feb 03;3(2):
pubmed: 25649250
Circulation. 1999 Mar 9;99(9):1183-9
pubmed: 10069786
J Appl Physiol (1985). 2004 Feb;96(2):754-61
pubmed: 14555683
Am J Physiol Heart Circ Physiol. 2017 Jan 1;312(1):H89-H97
pubmed: 27836894
Sleep. 2013 Jan 01;36(1):41-9
pubmed: 23288970
J Neurophysiol. 1974 Nov;37(6):1287-96
pubmed: 4436701
J Appl Physiol (1985). 2022 Jan 1;132(1):199-208
pubmed: 34941435
Am J Pathol. 2004 Jun;164(6):1875-82
pubmed: 15161623
Am J Physiol Regul Integr Comp Physiol. 2016 Dec 1;311(6):R1060-R1067
pubmed: 27707723
Am Rev Respir Dis. 1992 Apr;145(4 Pt 1):841-5
pubmed: 1554212
Sleep. 1999 Aug 1;22(5):667-89
pubmed: 10450601
Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H976-H984
pubmed: 32142377
J Appl Physiol (1985). 2014 Apr 15;116(8):1096-104
pubmed: 24557801
Exp Physiol. 2007 Jan;92(1):45-50
pubmed: 17099063