Galanin System in the Human Bile Duct and Perihilar Cholangiocarcinoma.


Journal

Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052

Informations de publication

Date de publication:
21 Jun 2023
Historique:
received: 21 04 2023
revised: 02 06 2023
accepted: 06 06 2023
medline: 17 7 2023
pubmed: 14 7 2023
entrez: 14 7 2023
Statut: epublish

Résumé

Perihilar cholangiocarcinoma (pCCA) is characterised by poor outcomes. Early diagnosis is essential for patient survival. The peptide galanin (GAL) and its receptors GAL Immunohistochemical staining was performed in healthy controls ( GAL and GAL Our in-depth characterisation of the GAL system in the healthy human biliary duct and pCCA in a small patient cohort revealed that GAL and GAL

Sections du résumé

BACKGROUND BACKGROUND
Perihilar cholangiocarcinoma (pCCA) is characterised by poor outcomes. Early diagnosis is essential for patient survival. The peptide galanin (GAL) and its receptors GAL
METHODS METHODS
Immunohistochemical staining was performed in healthy controls (
RESULTS RESULTS
GAL and GAL
CONCLUSIONS CONCLUSIONS
Our in-depth characterisation of the GAL system in the healthy human biliary duct and pCCA in a small patient cohort revealed that GAL and GAL

Identifiants

pubmed: 37443714
pii: cells12131678
doi: 10.3390/cells12131678
pmc: PMC10340323
pii:
doi:

Substances chimiques

Galanin 88813-36-9
Peptide Hormones 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Paracelsus Medical University
ID : R20/01/128-VAM
Organisme : Land Salzburg
ID : WISS 2025 F 2000237-FIP "STEBS".

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Auteurs

Sara Huber (S)

Research Program for Receptor Biochemistry and Tumor Metabolism, Department of Pediatrics, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria.

Theresia Fitzner (T)

Research Program for Receptor Biochemistry and Tumor Metabolism, Department of Pediatrics, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria.

René G Feichtinger (RG)

Department of Pediatrics, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria.

Sarah Hochmann (S)

Cell Therapy Institute, Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, 5020 Salzburg, Austria.

Theo Kraus (T)

Department of Pathology, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria.

Karl Sotlar (K)

Department of Pathology, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria.

Barbara Kofler (B)

Research Program for Receptor Biochemistry and Tumor Metabolism, Department of Pediatrics, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria.

Martin Varga (M)

Department of Surgery, University Hospital of the Paracelsus Medical University, 5020 Salzburg, Austria.

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Classifications MeSH