Chronic Mg


Journal

Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052

Informations de publication

Date de publication:
05 Jul 2023
Historique:
received: 02 06 2023
revised: 28 06 2023
accepted: 03 07 2023
medline: 17 7 2023
pubmed: 14 7 2023
entrez: 14 7 2023
Statut: epublish

Résumé

Magnesium is an essential mediator of a vast number of critical enzymatic cellular reactions in the human body. Some clinical epidemiological studies suggest that hypomagnesemia accounts for declines in insulin secretion in patients with type 2 diabetes (T2D); however, the results of various experimental studies do not support this notion. To address this discrepancy, we assessed the short- and long-term effects of hypomagnesemia on β-cell function and insulin secretion in primary mouse islets of Langerhans and in a mouse model of hypomagnesemia known as

Identifiants

pubmed: 37443824
pii: cells12131790
doi: 10.3390/cells12131790
pmc: PMC10340716
pii:
doi:

Substances chimiques

Insulin 0
Glucose IY9XDZ35W2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : Project-ID 239283807 - TRR-152 (P23, P15)

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Auteurs

Noushafarin Khajavi (N)

Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80539 Munich, Germany.

Klea Riçku (K)

Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80539 Munich, Germany.

Pascale C F Schreier (PCF)

Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80539 Munich, Germany.

Tanja Gentz (T)

Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80539 Munich, Germany.

Philipp Beyerle (P)

Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80539 Munich, Germany.

Emmanuel Cruz (E)

Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80539 Munich, Germany.

Andreas Breit (A)

Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80539 Munich, Germany.

Peter S Reinach (PS)

Ophthalmology Department, Wenzhou Medical University, Wenzhou 325015, China.

Thomas Gudermann (T)

Walther Straub Institute of Pharmacology and Toxicology, LMU Munich, 80539 Munich, Germany.
German Center for Lung Research, 81377 Munich, Germany.

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Classifications MeSH