Treatment of Recurrent Giant Cell Tumor of Bones: A Systematic Review.
adjuvant therapy
curettage
en-bloc resection
giant cell tumor
recurrence rate
second recurrence
treatment
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
22 Jun 2023
22 Jun 2023
Historique:
received:
14
05
2023
revised:
27
05
2023
accepted:
20
06
2023
medline:
14
7
2023
pubmed:
14
7
2023
entrez:
14
7
2023
Statut:
epublish
Résumé
The giant cell tumor of bones (GCTB) is a benign bone tumor with high postoperative recurrence potential. No specific treatment protocol has been developed to date in case of tumor recurrence, and the kind of re-operative surgery depends upon the surgeon's preferences. The aim of this systematic review is to determine the second recurrence rate and the respective functional results of the available treatment options applied to recurrent GCTB. Medline/PubMed and Scopus were searched to identify articles published until March 2023. Twelve studies fulfilled the inclusion criteria, comprising 458 patients suffering from recurrent GCTB. The overall incidence of second recurrence was 20.5%, at a mean interval of 28.8 months after the first surgery, and it was more evident after intralesional curettage (IC) surgery than en-bloc resection (EBR) (
Identifiants
pubmed: 37444396
pii: cancers15133287
doi: 10.3390/cancers15133287
pmc: PMC10340062
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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