Time-Dependent Changes of Klotho and FGF-23 Levels after Kidney Transplantation: Role of Cold Ischemia Time, Renal Function and Graft Inflammation.
cold ischemia time
graft function
graft subclinical inflammation
kidney transplant
serum FGF-23 levels
serum klotho levels
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
04 Jul 2023
04 Jul 2023
Historique:
received:
02
06
2023
revised:
23
06
2023
accepted:
30
06
2023
medline:
14
7
2023
pubmed:
14
7
2023
entrez:
14
7
2023
Statut:
epublish
Résumé
We investigated the evolution of serum klotho (s-Kl) and FGF-23 during the first two years post-kidney transplantation (KT), considering the cold ischemia time (CIT), glomerular filtration rate (GFR) and graft subclinical inflammation (SCI). We undertook a prospective, cohort, multicenter study of consecutive patients between April 2018 and January 2021 (with follow-up at 24 months). Subgroups were analyzed according to the median CIT (<14 vs. ≥14 h), the median GFR (≤40 vs. >40 mL/min/1.73 m
Identifiants
pubmed: 37445521
pii: jcm12134486
doi: 10.3390/jcm12134486
pmc: PMC10342325
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Instituto de Salud Carlos III
ID : PI17/02043
Organisme : Instituto de Salud Carlos III
ID : ICI21/00042
Organisme : Instituto de Salud Carlos III
ID : PI21/00251
Organisme : Instituto de Salud Carlos III
ID : RD16/0009/0006
Organisme : Instituto de Salud Carlos III
ID : RD16/0009/0031
Organisme : Instituto de Salud Carlos III
ID : RD21/0005/0012
Organisme : Instituto de Salud Carlos III
ID : RD21/0005/0008
Organisme : Instituto de Salud Carlos III
ID : RD21/0005/0001
Organisme : MICINN Ramon y Cajal program
ID : RYC2018-024461-I
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