Visceral Obesity and Cytokeratin-18 Antigens as Early Biomarkers of Liver Damage.
Cytokeratin-18
non-alcoholic fatty liver disease
visceral obesity
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
29 Jun 2023
29 Jun 2023
Historique:
received:
31
05
2023
revised:
28
06
2023
accepted:
28
06
2023
medline:
17
7
2023
pubmed:
14
7
2023
entrez:
14
7
2023
Statut:
epublish
Résumé
Visceral obesity is linked to the progression of fatty liver to nonalcoholic steatohepatitis (NASH). Cytokeratin-18 (CK18) epitopes M30 (CK18M30) and M65 (CK18M65) represent accurate markers for detecting NASH. The aim of this study was to evaluate the association of CK18M30 and CK18M65 levels with anthropometric and metabolic characteristics, liver stiffness, and liver indices of steatosis and fibrosis in a cohort of subjects with visceral obesity; in this cross-sectional study, transient elastography (TE-Fibroscan
Identifiants
pubmed: 37446065
pii: ijms241310885
doi: 10.3390/ijms241310885
pmc: PMC10341576
pii:
doi:
Substances chimiques
Keratin-18
0
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministero dell'istruzione, dell'Università e della Ricerca
ID : PRIN2017 E64I19000590001
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