Multilevel analysis identifying the factors associated with RSV detection in infants admitted for viral bronchiolitis in the era of the COVID-19 pandemic.
acute respiratory infections
air pollution
low-to-middle income countries
meteorological factors
respiratory syncytial virus
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
revised:
29
05
2023
received:
12
03
2023
accepted:
02
07
2023
medline:
23
10
2023
pubmed:
14
7
2023
entrez:
14
7
2023
Statut:
ppublish
Résumé
To identify factors independently associated with respiratory syncytial virus (RSV) detection in infants admitted for viral bronchiolitis during 3 consecutive years, before and during the COVID-19 pandemic, in Bogota, Colombia, a middle-income country with a subtropical highland climate. An analytical cross-sectional study was conducted before and during the COVID-19 pandemic, including patients with a diagnosis of viral bronchiolitis admitted to all the hospitals of the city between January 2019 and November 2021. We evaluated a set of a priori-selected predictor variables that included individual, healthcare system, meteorological, air pollutant, and COVID-19 variables. Since the variables analyzed are hierarchical in nature, multilevel modeling was used to identify factors independently associated with detection of RSV as the causative agent of viral bronchiolitis. A total of 13,177 patients were included in the study. After controlling for potential confounders, it was found that age (odds ratio [OR] 0.86; 95% confidence interval [CI] 0.76-0.97), a third level of medical care institution (OR 3.05; 95% CI 1.61-5.76), temperature (OR 1.60; 95% CI 1.24-2.07), rainfall (OR 1.003, 95% CI 1.001, 1.005), NO The identified factors associated with RSV detection provide additional scientific evidence that may be useful in the development of specific interventions aimed at ameliorating or preventing the impact of RSV in Bogota and probably other similar low- to middle-income countries in high-risk infants.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2795-2803Informations de copyright
© 2023 Wiley Periodicals LLC.
Références
Paulson KR, Kamath AM, Alam T, et al. Global, regional, and national progress towards sustainable development goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019. Lancet. 2021;398(10303):870-905.
Mazur NI, Löwensteyn YN, Willemsen JE, et al. Global respiratory syncytial virus-related infant community deaths. Clin Infect Dis. 2021;73(suppl 3):S229-S237.
Paramore LC, Ciuryla V, Ciesla G, Liu L. Economic impact of respiratory syncytial virus-related illness in the US: an analysis of national databases. Pharmacoeconomics. 2004;22(5):275-284.
Stein RT, Bont LJ, Zar H, et al. Respiratory syncytial virus hospitalization and mortality: systematic review and meta-analysis. Pediatr Pulmonol. 2017;52(4):556-569.
Villamil JPS, Polack FP, Buendía JA. Disability-adjusted life years for respiratory syncytial virus in children under 2 years. BMC Public Health. 2020;20(1):1679.
Fujiogi M, Goto T, Yasunaga H, et al. Trends in bronchiolitis hospitalizations in the United States: 2000-2016. Pediatrics. 2019;144(6):e20192614.
Rodríguez DA, Rodríguez-Martínez CE, Cárdenas AC, et al. Predictors of severity and mortality in children hospitalized with respiratory syncytial virus infection in a tropical region. Pediatr Pulmonol. 2014;49(3):269-276.
Welliver R. The relationship of meteorological conditions to the epidemic activity of respiratory syncytial virus. Paediatr Respir Rev. 2009;10(suppl 1):6-8.
Yusuf S, Piedimonte G, Auais A, et al. The relationship of meteorological conditions to the epidemic activity of respiratory syncytial virus. Epidemiol Infect. 2007;135(7):1077-1090.
Gamba-Sanchez N, Rodriguez-Martinez CE, Sossa-Briceño MP. Epidemic activity of respiratory syncytial virus is related to temperature and rainfall in equatorial tropical countries. Epidemiol Infect. 2016;144(10):2057-2063.
Rodriguez-Martinez CE, Sossa-Briceño MP, Acuña-Cordero R. Relationship between meteorological conditions and respiratory syncytial virus in a tropical country. Epidemiol Infect. 2015;143(12):2679-2686.
Guitart C, Bobillo-Perez S, Alejandre C, et al. Bronchiolitis, epidemiological changes during the SARS-CoV-2 pandemic. BMC Infect Dis. 2022;22(1):84.
Gastaldi A, Donà D, Barbieri E, Giaquinto C, Bont LJ, Baraldi E. COVID-19 lesson for respiratory syncytial virus (RSV): hygiene works. Children. 2021;8(12):1144.
Sullivan SG, Carlson S, Cheng AC, et al. Where has all the influenza gone? The impact of COVID-19 on the circulation of influenza and other respiratory viruses, Australia, March to September 2020. Euro Surveill. 2020;25(47):2001847.
Sistema de Vigilancia de la Gripe en España. Vigilancia centinela de infección respiratoria aguda en atención primaria (IRAs) y en hospitales (IRAG) Gripe, COVID-19 y otros virus respiratorios. 2021. Accessed February 27, 2022. https://vgripe.isciii.es/documentos/20202021/boletines/Informe%20semanal%20SVGE%20y%20otros%20virus%20respiratorios
Agha R, Avner JR. Delayed seasonal RSV surge observed during the COVID-19 pandemic. Pediatrics. 2021;148(3):e2021052089.
Yeoh DK, Foley DA, Minney-Smith CA, et al. Impact of coronavirus disease 2019 public health measures on detections of influenza and respiratory syncytial virus in children during the 2020 Australian winter. Clin Infect Dis. 2021;72(12):2199-2202.
Britton PN, Hu N, Saravanos G, et al. COVID-19 public health measures and respiratory syncytial virus. Lancet Child Adolesc Health. 2020;4(11):42.
Delestrain C, Danis K, Hau I, et al. Impact of COVID-19 social distancing on viral infection in France: a delayed outbreak of RSV. Pediatr Pulmonol. 2021;56(12):3669-3673.
Weinberger Opek M, Yeshayahu Y, Glatman-Freedman A, Kaufman Z, Sorek N, Brosh-Nissimov T. Delayed respiratory syncytial virus epidemic in children after relaxation of COVID-19 physical distancing measures, Ashdod, Israel, 2021. Euro Surveill. 2021;26(29):2100706.
Karr CJ, Demers PA, Koehoorn MW, Lencar CC, Tamburic L, Brauer M. Influence of ambient air pollutant sources on clinical encounters for infant bronchiolitis. Am J Respir Crit Care Med. 2009;180(10):995-1001.
Liu Y, Zhou Y, Lu J. Exploring the relationship between air pollution and meteorological conditions in China under environmental governance. Sci Rep. 2020;10(1):14518.
Loaiza-Ceballos MC, Marin-Palma D, Zapata W, Hernandez JC. Viral respiratory infections and air pollutants. Air Qual Atmos Health. 2022;15(1):105-114.
Nenna R, Evangelisti M, Frassanito A, et al. Respiratory syncytial virus bronchiolitis, weather conditions and air pollution in an Italian urban area: an observational study. Environ Res. 2017;158:188-193.
Suh M, Movva N, Jiang X, et al. Respiratory syncytial virus burden and healthcare utilization in United States infants <1 year of age: study of Nationally Representative Databases, 2011-2019. J Infect Dis. 2022;226(suppl 2):184.
Dominski FH, Lorenzetti Branco JH, Buonanno G, Stabile L, Gameiro da Silva M, Andrade A. Effects of air pollution on health: a mapping review of systematic reviews and meta-analyses. Environ Res. 2021;201:111487.
Karr CJ, Rudra CB, Miller KA, et al. Infant exposure to fine particulate matter and traffic and risk of hospitalization for RSV bronchiolitis in a region with lower ambient air pollution. Environ Res. 2009;109(3):321-327.
Instituto distrital de gestión de riesgos y cambio climático. Lluvias y temperatura en Bogotá desde 1979 a 2018. https://www.idiger.gov.co/precipitacion-y-temperatura#:~:text=De%20acuerdo%20con%20el%20Instituto,promedio%20anual%20de%20840%20mm
Climate of Colombia. Encyclopaedia Britannica. Accessed May 28, 2023. https://www.britannica.com/place/Colombia.
Inventario de emisiones de Bogotá. Contaminantes atmosféricos. Secretaría de Ambiente de Bogotá. Alcaldía mayor de Bogotá. Accessed March 7, 2022. https://www.ambientebogota.gov.co/documents/10184/397082/Inventario+de+Emisiones+de+Bogota+portal+nuevo.pdf/972994eb-7f58-42c2-a801-0f8579937919
Montaño JI, Rengifo H, Rivillas JC, Ospina ML. Knowledge management and information resources for health in Colombia. Strateg Monit. 2013;4:49-55.
Galindo ACE, Rivera ANM, Montaño JI, Correa MMM. Information release: the key in knowledge management for health in Colombia. Strateg Monitor. 2014;5:article 8992.
Barengo NC, Tamayo DC. Reported diabetes mellitus prevalence rates in the Colombia healthcare system from 2009 to 2012: analysis by regions using data of the official information sources. Int J Endocrinol. 2015;2015:1-7.
Secretaría de Salud. Alcaldía mayor de Bogotá. Accessed February 27, 2022. http://www.saludcapital.gov.co/Paginas2/Inicio.aspx
Ralston SL, Lieberthal AS, Meissner HC, et al. Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis. Pediatrics. 2014;134(5):e1474-e1502.
Red de monitoreo de calidad de aire de Bogotá (RMCAB). Alcaldía mayor de Bogotá. Secretaría de ambient. Accessed February 27, 2022. http://rmcab.ambientebogota.gov.co/home/map
Aranda J, Rodriguez C, Corredor J, García A Design of an air quality monitoring system and early alerts based on IoT and AI for Bogotá city. 2021.
Quality Assurance Handbook for Air Pollution Measurement Systems. United States Environmental Protection Agency. Accessed January 8, 2023. https://www3.epa.gov/ttnamti1/files/ambient/pm25/qa/Final%20Handbook%20Document%201_17.pdf
Stata multilevel mixed-effects. Reference manual - release 15. Accessed April 12th, 2023. https://www.stata-press.com/data/r15/me.html
Schwarz G. Estimating the dimension of a model. Ann Stat. 1978;6:461-464.
Sarmadi M, Rahimi S, Rezaei M, Sanaei D, Dianatinasab M. Air quality index variation before and after the onset of COVID-19 pandemic: a comprehensive study on 87 capital, industrial and polluted cities of the world. Environ Sci Eur. 2021;33(1):134.
Göthe CJ, Fristedt B, Sundell L, Kolmodin B, Ehrner-Samuel H, Göthe K. Carbon monoxide hazard in city traffic. An examination of traffic policemen in three Swedish towns. Arch Environ Health. 1969;19(3):310-314.
Feiler MO, Yucel R, Liu Z, et al. Trends and non-clinical predictors of respiratory syncytial virus (RSV) and influenza diagnosis in an urban pediatric population. Int J Pediatr Res. 2023;9(1):112.
Moe N, Pedersen B, Nordbø SA, et al. Respiratory virus detection and clinical diagnosis in children attending day care. PLoS One. 2016;11(7):e0159196.
Márquez Caballero J, Cordero Matía ME. Epidemiology of acute bronchiolitis in a third-level hospital during the COVID-19 pandemic. Arch Bronconeumol. 2023;59(4):264-266.
HEI Collaborative Working Group on Air Pollution, Poverty, and Health in Ho Chi, Minh C, Le TG, Ngo L, et al. Effects of short-term exposure to air pollution on hospital admissions of young children for acute lower respiratory infections in ho chi minh city, Vietnam. Res Rep Health Eff Inst. 2012;(169):5-72.
Lee MH, Mailepessov D, Yahya K, Loo LH, Maiwald M, Aik J. Air quality, meteorological variability and pediatric respiratory syncytial virus infections in Singapore. Sci Rep. 2023;13(1):1001.
Tian L, Qiu H, Pun VC, et al. Ambient carbon monoxide associated with reduced risk of hospital admissions for respiratory tract infections. Am J Respir Crit Care Med. 2013;188(10):1240-1245.
Chin BY, Otterbein LE. Carbon monoxide is a poison… to microbes! CO as a bactericidal molecule. Curr Opin Pharmacol. 2009;9(4):490-500.
Nobre S, Seixas D, Romão CC, Saraiva M. Antimicrobial action of carbon monoxide-releasing compounds. Antimicrob Agents Chemother. 2007;51(12):4303-4307.