The biological sample collection of the OFSEP French MS registry: An essential tool dedicated to researchers.

Today's medicine strives to be personalized, preventive, predictive and participatory. This implies to have access to multimodal data to better characterize patients groups and to combine clinical and imaging data with high-quality biological samples. Collecting such data is one of the objectives of the Observatoire français de la sclérose en plaques (OFSEP), the French MS registry. On December 2022, the OFSEP biocollection includes 4,888 patients with scientific characteristics and about 90,000 samples. Thanks to its richness, this biocollection open for the scientific community, contributes to address unmet needs in MS through identification of multiomics determinants of MS activity, progression and secondary effects.

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Copyright © 2023. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Laure Michel reports a relationship with Biogen that includes: consulting or advisory. Laure Michel reports a relationship with Teva Health that includes: consulting or advisory. Laure Michel reports a relationship with Roche that includes: consulting or advisory. Laure Michel reports a relationship with Sanofi Genzyme that includes: consulting or advisory. Laure Michel reports a relationship with Janssen Pharmaceuticals Inc that includes: consulting or advisory. Laure Michel reports a relationship with Novartis that includes: consulting or advisory. Laure Michel reports a relationship with Merck & Co Inc that includes: consulting or advisory. Eric Thouvenot reports a relationship with Actelion Ltd that includes: consulting or advisory, speaking and lecture fees, and travel reimbursement. Eric Thouvenot reports a relationship with Biogen that includes: consulting or advisory, speaking and lecture fees, and travel reimbursement. Eric Thouvenot reports a relationship with Bristol Myers Squibb Co that includes: consulting or advisory, speaking and lecture fees, and travel reimbursement. Eric Thouvenot reports a relationship with Merck & Co Inc that includes: consulting or advisory, speaking and lecture fees, and travel reimbursement. Eric Thouvenot reports a relationship with Novartis that includes: consulting or advisory, speaking and lecture fees, and travel reimbursement. Eric Thouvenot reports a relationship with Roche that includes: consulting or advisory, speaking and lecture fees, and travel reimbursement. Sandra Vukusic reports a relationship with Biogen Inc that includes: speaking and lecture fees and travel reimbursement. Sandra Vukusic reports a relationship with Bristol Myers Squibb Co that includes: speaking and lecture fees and travel reimbursement. Sandra Vukusic reports a relationship with Janssen Pharmaceuticals Inc that includes: speaking and lecture fees and travel reimbursement. Sandra Vukusic reports a relationship with Merck & Co Inc that includes: speaking and lecture fees and travel reimbursement. Sandra Vukusic reports a relationship with Novartis that includes: speaking and lecture fees and travel reimbursement. Sandra Vukusic reports a relationship with Roche that includes: speaking and lecture fees and travel reimbursement. Sandra Vukusic reports a relationship with Sandoz Inc that includes: speaking and lecture fees and travel reimbursement. Sandra Vukusic reports a relationship with Sanofi Genzyme that includes: speaking and lecture fees and travel reimbursement. Helene Zephir reports a relationship with Alexion that includes: consulting or advisory. Helene Zephir reports a relationship with Biogen Inc that includes: consulting or advisory. Helene Zephir reports a relationship with Horizon Therapeutics plc that includes: consulting or advisory. Helene Zephir reports a relationship with Merck & Co Inc that includes: consulting or advisory. Helene Zephir reports a relationship with Novartis that includes: consulting or advisory. Helene Zephir reports a relationship with Sanofi that includes: consulting or advisory. Helene Zephir reports a relationship with Roche that includes: consulting or advisory and funding grants. Helene Zephir reports a relationship with Foundation for Help in Research of Multiple Sclerosis that includes: funding grants.