Management of Coronary Artery Spasm.

Coronary artery spasm treatment variant angina vasospastic angina

Journal

European cardiology

ISSN: 1758-3764

Titre abrégé: Eur Cardiol

Pays: England

ID NLM: 101574780

Informations de publication

Date de publication:
2023

Historique:

received: 24 09 2022

accepted: 14 11 2022

medline: 17 7 2023

pubmed: 17 7 2023

entrez: 17 7 2023

Statut: epublish

Résumé

Calcium channel blockers (CCBs) are the first-line treatment for coronary artery spasm (CAS). When CAS-related angina symptoms are not well controlled by CCB therapy, long-acting nitrates or (where available) nicorandil can be added as second-line medications. In the case of CAS refractory to standard treatments, several other alternative drugs and interventions have been proposed, including the Rho-kinase inhibitor fasudil, anti-adrenergic drugs, neural therapies and percutaneous coronary interventions. In patients with syncope or cardiac arrest caused by CAS-related tachyarrhythmias, or even bradyarrhythmias, implantation of an ICD or pacemaker, respectively, should be considered according to the risk of recurrence and efficacy of vasodilator therapy.

Identifiants

DOI: 10.15420/ecr.2022.47 PMID: 37456765 PMC: PMC10345953

pubmed: 37456765

doi: 10.15420/ecr.2022.47

pmc: PMC10345953

doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

e38

Informations de copyright

Déclaration de conflit d'intérêts

Disclosures: GAL and HS are on the European Cardiology Review editorial board; this did not influence peer review. The authors have no other conflicts of interest to declare.

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