A new
Cyclotron
Iodine-123 production
Proton beam
Radioisotope production
Targetry
Journal
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
ISSN: 1872-9800
Titre abrégé: Appl Radiat Isot
Pays: England
ID NLM: 9306253
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
13
03
2023
revised:
22
06
2023
accepted:
04
07
2023
medline:
5
9
2023
pubmed:
17
7
2023
entrez:
17
7
2023
Statut:
ppublish
Résumé
Since 2001, Nuclear and Energy Research Institute IPEN-CNEN has produced weekly ultrapure iodine-123, using a manual irradiation system, fully developed in IPEN. Iodine-123 radiopharmaceuticals have been produced and distributed to hospitals and clinics of nuclear medicine, where several diagnostic imaging procedures for thyroid, brain and cardiovascular functions are performed. Due to the short half-life and emission of low-energy photons, this radioisotope becomes suitable for diagnosis in children. In the present work, the technical and constructive aspects of a new fully automated irradiation system, dedicated to
Identifiants
pubmed: 37459684
pii: S0969-8043(23)00279-8
doi: 10.1016/j.apradiso.2023.110926
pii:
doi:
Substances chimiques
Iodine-123
8YWR746RPQ
Iodine Radioisotopes
0
Radiopharmaceuticals
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110926Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.