Association of dietary insulinemic and inflammatory potential with risk of liver cancer and chronic liver disease mortality in postmenopausal women: a prospective cohort study.

Humans Female Prospective Studies Postmenopause Feeding Behavior Diet / adverse effects Liver Neoplasms / etiology Risk Factors Cohort Studies Inflammation / complications Hyperinsulinism / complications
EDIH EDIP chronic liver diseases empirical dietary index for hyperinsulinemia empirical dietary inflammation pattern liver cancer mortality prospective cohort study

Journal

The American journal of clinical nutrition
ISSN: 1938-3207
Titre abrégé: Am J Clin Nutr
Pays: United States
ID NLM: 0376027

Informations de publication

Date de publication:
09 2023
Historique:
received: 04 04 2023
revised: 07 07 2023
accepted: 13 07 2023
pmc-release: 17 07 2024
medline: 5 9 2023
pubmed: 18 7 2023
entrez: 17 7 2023
Statut: ppublish

Résumé

Low diet quality, diabetes, and chronic inflammation are risk factors of liver cancer and chronic liver disease (CLD), but the extent to which insulinemic and inflammatory diets are independently associated with risk of liver cancer and CLD mortality is unknown. We conducted a prospective cohort analysis among 78,356 postmenopausal women in the Women's Health Initiative Observational Study. Two validated dietary indices, the empirical dietary index for hyperinsulinemia (EDIH) and the empirical dietary inflammation pattern (EDIP), were estimated from a food-frequency questionnaire. Incident cases of liver cancer and CLD mortality were adjudicated via review of medical records and linkage to National Death Index. Multivariable hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using Cox proportional hazards models, adjusted for age, diabetes, body mass index, and other covariates. During a median 22.1 y of follow-up, we documented 176 primary liver cancer cases and 156 CLD mortality cases. EDIH was positively associated with incident liver cancer (HR Dietary insulinemic and inflammatory potentials were independently associated with higher risk of liver cancer and CLD mortality in U.S. postmenopausal women. These findings suggest a potential role for diet modification to reduce risk of liver cancer and CLD.

Sections du résumé

BACKGROUND
Low diet quality, diabetes, and chronic inflammation are risk factors of liver cancer and chronic liver disease (CLD), but the extent to which insulinemic and inflammatory diets are independently associated with risk of liver cancer and CLD mortality is unknown.
METHODS
We conducted a prospective cohort analysis among 78,356 postmenopausal women in the Women's Health Initiative Observational Study. Two validated dietary indices, the empirical dietary index for hyperinsulinemia (EDIH) and the empirical dietary inflammation pattern (EDIP), were estimated from a food-frequency questionnaire. Incident cases of liver cancer and CLD mortality were adjudicated via review of medical records and linkage to National Death Index. Multivariable hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using Cox proportional hazards models, adjusted for age, diabetes, body mass index, and other covariates.
RESULTS
During a median 22.1 y of follow-up, we documented 176 primary liver cancer cases and 156 CLD mortality cases. EDIH was positively associated with incident liver cancer (HR
CONCLUSIONS
Dietary insulinemic and inflammatory potentials were independently associated with higher risk of liver cancer and CLD mortality in U.S. postmenopausal women. These findings suggest a potential role for diet modification to reduce risk of liver cancer and CLD.

Identifiants

DOI: 10.1016/j.ajcnut.2023.07.009 PMID: 37460062 PMC: PMC10517210
pubmed: 37460062
pii: S0002-9165(23)66030-7
doi: 10.1016/j.ajcnut.2023.07.009
pmc: PMC10517210
pii:
doi:

Types de publication

Observational Study Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

530-537

Subventions

Organisme : NHLBI NIH HHS
ID : HHSN268201600001C
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600003C
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA272452
Pays : United States
Organisme : NCI NIH HHS
ID : R21 CA252962
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600004C
Pays : United States
Organisme : NCI NIH HHS
ID : R21 CA238651
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600002C
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA259208
Pays : United States
Organisme : NCI NIH HHS
ID : R37 CA262299
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201600018C
Pays : United States

Informations de copyright

Copyright © 2023 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.

Références

Pancreas. 2004 Oct;29(3):231-8
pubmed: 15367890
J Nutr. 2016 Aug;146(8):1560-70
pubmed: 27358416
Int J Cancer. 2020 Aug 15;147(4):1050-1058
pubmed: 32142166
Ann Epidemiol. 2003 Oct;13(9 Suppl):S18-77
pubmed: 14575939
Lancet Gastroenterol Hepatol. 2020 Mar;5(3):245-266
pubmed: 31981519
Oxid Med Cell Longev. 2016;2016:4234061
pubmed: 28070230
Cancer Sci. 2010 May;101(5):1073-9
pubmed: 20345478
Hepatology. 2018 Jan;67(1):123-133
pubmed: 28802062
J Hepatol. 2019 Apr;70(4):674-683
pubmed: 30543829
J Womens Health (Larchmt). 2017 Dec;26(12):1270-1277
pubmed: 28933583
Cancer Res. 2016 Oct 15;76(20):6076-6083
pubmed: 27742674
J Natl Cancer Inst. 2020 Feb 1;112(2):170-178
pubmed: 31184362
Metabolites. 2019 Jun 24;9(6):
pubmed: 31238601
Ann Epidemiol. 2003 Oct;13(9 Suppl):S122-8
pubmed: 14575944
Ann Epidemiol. 1999 Apr;9(3):178-87
pubmed: 10192650
Int J Cancer. 2021 May 1;148(9):2102-2114
pubmed: 33129230
Front Nutr. 2021 Sep 20;8:690428
pubmed: 34616762
Cancer Epidemiol Biomarkers Prev. 2021 Jun;30(6):1229-1240
pubmed: 33827986
Control Clin Trials. 1998 Feb;19(1):61-109
pubmed: 9492970
Cancer. 2016 May 1;122(9):1312-37
pubmed: 26959385
J Hepatol. 2019 Jan;70(1):151-171
pubmed: 30266282
Womens Health (Lond). 2009 Mar;5(2):191-203
pubmed: 19245356
J Nutr. 2018 May 1;148(5):771-780
pubmed: 29897561
Hepatology. 2019 Aug;70(2):577-586
pubmed: 30506561
Hepatology. 2014 Aug;60(2):588-97
pubmed: 24715615
BMJ. 2018 Jul 18;362:k2817
pubmed: 30021785
Eur J Epidemiol. 2005;20(7):575-9
pubmed: 16119429
Cancer Epidemiol Biomarkers Prev. 2021 Apr;30(4):789-796
pubmed: 33514605
World J Gastroenterol. 2015 Jul 7;21(25):7613-20
pubmed: 26167064
World J Gastroenterol. 2018 Aug 28;24(32):3663-3670
pubmed: 30166861
Hepatol Commun. 2019 Jan 31;3(3):437-447
pubmed: 30859154
J Clin Invest. 2006 Jul;116(7):1793-801
pubmed: 16823477
Hepatol Res. 2013 Jan;43(1):51-64
pubmed: 23332087
Br J Nutr. 2016 Nov 28;116(10):1787-1798
pubmed: 27821188
Public Health Nutr. 2014 Aug;17(8):1689-96
pubmed: 23941862

Auteurs

Xinyuan Zhang (X)

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.

Longgang Zhao (L)

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States; Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States.

Cami N Christopher (CN)

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.

Fred K Tabung (FK)

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States; Department of Internal Medicine, The Ohio State University College of Medicine and Comprehensive Cancer Center, Columbus, OH, United States.

Wei Bao (W)

Institute of Public Health, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

David O Garcia (DO)

Department of Health Promotion Sciences, Mel & Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, United States.

Aladdin H Shadyab (AH)

Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, United States.

Nazmus Saquib (N)

Department of Clinical Sciences, College of Medicine, Sulaiman AlRajhi University, Al Bukayriyah, Saudi Arabia.

Marian L Neuhouser (ML)

Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States.

Lesley F Tinker (LF)

Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, United States.

Xuehong Zhang (X)

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States. Electronic address: xuehong.zhang@channing.harvard.edu.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Association of dietary insulinemic and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Association of dietary insulinemic and...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Développement sexuel › Climatère › Ménopause › Post-ménopause › Association of dietary insulinemic and...
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Comportement alimentaire › Association of dietary insulinemic and...
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Régime alimentaire › Association of dietary insulinemic and...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Association of dietary insulinemic and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Association of dietary insulinemic and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Association of dietary insulinemic and...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Association of dietary insulinemic and...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles du métabolisme du glucose › Hyperinsulinisme › Association of dietary insulinemic and...