Three small partner proteins facilitate the type VII-dependent secretion export of an antibacterial nuclease.
Staphylococcus aureus
Type VII secretion system
effector protein
nuclease toxin
pre-secretion complex
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
08 Jun 2023
08 Jun 2023
Historique:
pubmed:
18
7
2023
medline:
18
7
2023
entrez:
18
7
2023
Statut:
epublish
Résumé
The type VIIb protein secretion system (T7SSb) plays a role in interbacterial competition in Gram-positive Firmicute bacteria and secretes various toxic effector proteins. The mechanism of secretion and the roles of numerous conserved genes within T7SSb gene clusters remain unknown. EsaD is a nuclease toxin secreted by the
Identifiants
pubmed: 37461441
doi: 10.1101/2023.04.01.535202
pmc: PMC10350083
pii:
doi:
Types de publication
Preprint
Langues
eng
Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Commentaires et corrections
Type : UpdateIn
Déclaration de conflit d'intérêts
Declarations of interest The authors declare no competing interests.