Spatial organization and function of RNA molecules within phase-separated condensates are controlled by Dnd1.

Dead end RNA translation Zebrafish germ cells germ granules nanos phase separation

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
09 Jul 2023
Historique:
pubmed: 18 7 2023
medline: 18 7 2023
entrez: 18 7 2023
Statut: epublish

Résumé

Germ granules, condensates of phase-separated RNA and protein, are organelles essential for germline development in different organisms The patterning of the granules and its relevance for germ cell fate are not fully understood. Combining three-dimensional

Identifiants

pubmed: 37461638
doi: 10.1101/2023.07.09.548244
pmc: PMC10350045
pii:
doi:

Types de publication

Preprint

Langues

eng

Commentaires et corrections

Type : UpdateIn

Déclaration de conflit d'intérêts

DECLARATION OF INTERESTS The authors declare that they have no competing interests.

Auteurs

Kim Joana Westerich (KJ)

Institute of Cell Biology, Center for Molecular Biology of Inflammation, University of Münster; 48149 Münster, Germany.

Katsiaryna Tarbashevich (K)

Institute of Cell Biology, Center for Molecular Biology of Inflammation, University of Münster; 48149 Münster, Germany.

Jan Schick (J)

Institute of Cell Biology, Center for Molecular Biology of Inflammation, University of Münster; 48149 Münster, Germany.

Antra Gupta (A)

Institute of Cell Biology, Center for Molecular Biology of Inflammation, University of Münster; 48149 Münster, Germany.

Mingzhao Zhu (M)

Department of Chemistry & Biochemistry and The Baylor Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, Texas 76706, United States.

Kenneth Hull (K)

Department of Chemistry & Biochemistry and The Baylor Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, Texas 76706, United States.

Daniel Romo (D)

Department of Chemistry & Biochemistry and The Baylor Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, Texas 76706, United States.

Dagmar Zeuschner (D)

Electron Microscopy Facility, Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany.

Mohammad Goudarzi (M)

Institute of Cell Biology, Center for Molecular Biology of Inflammation, University of Münster; 48149 Münster, Germany.

Theresa Gross-Thebing (T)

Institute of Cell Biology, Center for Molecular Biology of Inflammation, University of Münster; 48149 Münster, Germany.

Erez Raz (E)

Institute of Cell Biology, Center for Molecular Biology of Inflammation, University of Münster; 48149 Münster, Germany.
Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany.

Classifications MeSH