Improved paediatric antimicrobial prescribing with a smartphone application: a before and after interventional study.


Journal

Archives of disease in childhood
ISSN: 1468-2044
Titre abrégé: Arch Dis Child
Pays: England
ID NLM: 0372434

Informations de publication

Date de publication:
11 2023
Historique:
received: 08 05 2023
accepted: 10 07 2023
medline: 1 11 2023
pubmed: 19 7 2023
entrez: 18 7 2023
Statut: ppublish

Résumé

Children have a high consumption of antimicrobials that require complicated decision-making by prescribers. Despite this, antimicrobial stewardship (AMS) interventions are often not translated into paediatric medicine. Script is a smartphone application (app) launched in Auckland, New Zealand to support decision-making for antimicrobial prescribers. The aim was to improve adherence to existing local clinical guidelines for both adult and paediatric infections. Inpatient and emergency department antimicrobial prescriptions were prospectively collected and evaluated for guideline adherence. Baseline prescribing data were collected and compared with prescribing at 4 months and 1 year after the app was launched. Prescriptions were graded as 'appropriate' or 'inappropriate' by investigators. Grading was done blinded to timing of the prescription relative to the intervention. Following the launch of the Script app, guideline adherence significantly increased from 241 of 348 (69%) antimicrobial prescriptions graded as appropriate during the baseline period to 301 of 359 (83%) after 4 months (p<0.0001). This improvement from baseline was sustained at 1 year with 263 of 323 (81%) adherence (p<0.001). At 1 year, this improvement could be demonstrated separately for medical, surgical and emergency department prescriptions. There was a significant and sustained improvement in adherence to paediatric antimicrobial guidelines following the introduction of a prescribing support app. The need to seek guidance for antimicrobial doses due to the age-based and weight-based calculations in paediatrics may mean that AMS interventions such as decision support and prescribing tools are particularly well suited to paediatric prescribing.

Identifiants

pubmed: 37463738
pii: archdischild-2023-325795
doi: 10.1136/archdischild-2023-325795
doi:

Substances chimiques

Anti-Infective Agents 0
Anti-Bacterial Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

899-903

Informations de copyright

© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Sarah Primhak (S)

Paediatric Infectious Diseases, Starship Children's Health, Auckland, New Zealand sprimhak@adhb.govt.nz.
Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

Natasha Pool (N)

Antimicrobial Stewardship Pharmacist, Starship Children's Health, Auckland, New Zealand.
Paediatrics, Middlemore Hospital, Auckland, New Zealand.

Michelle Shien Yee Sam (MSY)

Paediatric Infectious Diseases, Starship Children's Health, Auckland, New Zealand.

Eamon Duffy (E)

Antimicrobial Stewardship Pharmacist, Auckland City Hospital, Auckland, New Zealand.

Stephen R Ritchie (SR)

Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Infectious Diseases, Auckland City Hospital, Auckland, New Zealand.

Rachel Webb (R)

Paediatric Infectious Diseases, Starship Children's Health, Auckland, New Zealand.
Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Paediatrics, Middlemore Hospital, Auckland, New Zealand.

Elizabeth Wilson (E)

Paediatric Infectious Diseases, Starship Children's Health, Auckland, New Zealand.

Lesley Voss (L)

Paediatric Infectious Diseases, Starship Children's Health, Auckland, New Zealand.

Emma J Best (EJ)

Paediatric Infectious Diseases, Starship Children's Health, Auckland, New Zealand.
Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

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