Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report.


Journal

Journal of clinical pathology
ISSN: 1472-4146
Titre abrégé: J Clin Pathol
Pays: England
ID NLM: 0376601

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 01 06 2023
accepted: 15 06 2023
medline: 23 10 2023
pubmed: 19 7 2023
entrez: 18 7 2023
Statut: ppublish

Résumé

Leptomeningeal involvement among non-small cell lung cancer (NSCLC) patients is an aggressive form of disease that requires quick and efficient treatment. In this case report, we describe a woman in her 40s with a presenting symptom of headache that ultimately was diagnosed as leptomeningeal spread from NSCLC adenocarcinoma. We identified EGFR mutation in less than 48 hours from the biopsy using imagene-artificial intelligence's real-time algorithmic solution on the pathological diagnostic slide.

Identifiants

pubmed: 37463768
pii: jcp-2023-208991
doi: 10.1136/jcp-2023-208991
pmc: PMC10646899
doi:

Substances chimiques

ErbB Receptors EC 2.7.10.1

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

790-792

Informations de copyright

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

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J Thorac Oncol. 2020 Apr;15(4):637-648
pubmed: 31887431
Lancet Digit Health. 2021 Mar;3(3):e195-e203
pubmed: 33478929
Radiat Oncol. 2020 Jul 31;15(1):185
pubmed: 32736566
J Clin Oncol. 2020 Feb 20;38(6):538-547
pubmed: 31809241
Lancet Oncol. 2018 Jan;19(1):e43-e55
pubmed: 29304362
Neuro Oncol. 2021 Sep 1;23(9):1447-1456
pubmed: 33908612
Curr Treat Options Oncol. 2020 Jul 28;21(9):72
pubmed: 32725549

Auteurs

Barliz Waissengrin (B)

Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel barlizw@tlvmc.gov.il.
School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Alexandra Garasimov (A)

Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Or Bainhoren (O)

Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Ofer Merimsky (O)

Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Sivan Shamai (S)

Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Ariel Erental (A)

School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Ido Wolf (I)

Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Dov Hershkovitz (D)

School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

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Classifications MeSH