Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
18 07 2023
Historique:
received: 23 05 2023
accepted: 13 07 2023
medline: 21 7 2023
pubmed: 19 7 2023
entrez: 18 7 2023
Statut: epublish

Résumé

Non-melanoma skin cancer (NMSC) is the most common cancer in Caucasians worldwide. We investigated the pathophysiological role of MIF and its homolog D-DT in UVB- and chemically induced NMSC using Mif

Identifiants

pubmed: 37464010
doi: 10.1038/s41598-023-38748-9
pii: 10.1038/s41598-023-38748-9
pmc: PMC10354066
doi:

Substances chimiques

dopachrome isomerase EC 5.3.3.12
Macrophage Migration-Inhibitory Factors 0
Mif protein, mouse EC 5.3.2.1

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

11611

Subventions

Organisme : NIAMS NIH HHS
ID : R01 AR078334
Pays : United States

Informations de copyright

© 2023. The Author(s).

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Auteurs

Sebastian Huth (S)

Department of Dermatology and Allergology, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany. shuth@ukaachen.de.

Laura Huth (L)

Department of Dermatology and Allergology, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.

Ruth Heise (R)

Department of Dermatology and Allergology, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.

Yvonne Marquardt (Y)

Department of Dermatology and Allergology, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.

Linda Lopopolo (L)

Department of Dermatology and Allergology, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.

Marta Piecychna (M)

Department of Medicine, Yale School of Medicine, New Haven, CT, USA.

Peter Boor (P)

Institute of Pathology and Department of Nephrology and Immunology, Medical Faculty, RWTH Aachen University, Aachen, Germany.

Günter Fingerle-Rowson (G)

Department I of Internal Medicine, Center of Integrated Oncology Köln Bonn, University Hospital of Cologne, Cologne, Germany.

Aphrodite Kapurniotu (A)

Division of Peptide Biochemistry, School of Life Sciences, Technical University of Munich (TUM), Freising, Germany.

Amir S Yazdi (AS)

Department of Dermatology and Allergology, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.

Richard Bucala (R)

Department of Medicine, Yale School of Medicine, New Haven, CT, USA.

Jürgen Bernhagen (J)

Division of Vascular Biology, Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-University (LMU), Munich, Germany.

Jens Malte Baron (JM)

Department of Dermatology and Allergology, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.

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Classifications MeSH