Subhallucinogenic Concentrations of Substituted Phenethylamines as a Novel Therapeutic Approach for Inflammatory and Neurological Disorders.


Journal

ACS medicinal chemistry letters
ISSN: 1948-5875
Titre abrégé: ACS Med Chem Lett
Pays: United States
ID NLM: 101521073

Informations de publication

Date de publication:
13 Jul 2023
Historique:
received: 20 05 2023
pmc-release: 13 07 2024
medline: 19 7 2023
pubmed: 19 7 2023
entrez: 19 7 2023
Statut: epublish

Résumé

This Patent Highlight presents a method to treat inflammatory or neurological disorders in subjects needing treatment. The method involves administering a therapeutically effective amount of a composition containing a subhallucinogenic concentration of substituted phenethylamine. The substituted phenethylamine may belong to the 2C-X family, including 2C-H, 2C-I, 2C-B, or 2C-E. The specific concentration depends on the chronic inflammation's severity, with 25 mg for mild, 50 mg for moderate, and 100 mg for severe cases.

Identifiants

pubmed: 37465310
doi: 10.1021/acsmedchemlett.3c00220
pmc: PMC10350937
doi:

Types de publication

Editorial

Langues

eng

Pagination

884-885

Informations de copyright

Published 2023 by American Chemical Society.

Déclaration de conflit d'intérêts

The author declares no competing financial interest.

Références

J Med Chem. 2023 Apr 13;66(7):4417-4433
pubmed: 36971365
Neuropharmacology. 2023 Feb 1;223:109257
pubmed: 36179919
Neuropharmacology. 2023 Mar 1;225:109375
pubmed: 36529260
J Transl Med. 2023 Feb 25;21(1):149
pubmed: 36829232
Biol Psychiatry. 2023 Jun 15;93(12):1061-1070
pubmed: 36715317
Drug Discov Today. 2023 Apr;28(4):103518
pubmed: 36758932

Auteurs

Robert B Kargbo (RB)

Usona Institute, Fitchburg, Wisconsin 53711-5300, United States.

Classifications MeSH